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位置: 首页> 品牌> Sigma-Aldrich> Anti-Potassium voltage-gated channel, shaker-related subfamily, β member 3

Anti-KCNAB3 antibody produced in rabbit

品牌
Sigma-Aldrich
货号
AV35151
规格纯度
IgG fraction of antiserum
价格
3311.54 *本价格含增值税费
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半岛bd体育手机客户端 名称:
Anti-KCNAB3 antibody produced in rabbit
Anti-Potassium voltage-gated channel, shaker-related subfamily, β member 3
半岛bd体育手机客户端 介绍:

半岛bd体育手机客户端 说明

一般描述

KCNAB3 codes for a member of potassium voltage-gated channel (shaker-related) protein subfamily. This protein is a β subunit and can form heterodimers that modulate the function of α subunits.
Rabbit Anti-KCNAB3 antibody recognizes rat, canine, human, bovine, and mouse KCNAB3.

免疫原

Synthetic peptide directed towards the N terminal region of human KCNAB3

应用

Rabbit Anti-KCNAB3 antibody is suitable for western blot (0.65 μg/ml) and IHC (4-8 μg/ml) applications.

生化/生理作用

Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. Four sequence-related potassium channel genes - shaker, shaw, shab, and shal - have been identified in Drosophila, and each has been shown to have human homolog(s). This gene encodes a member of the potassium channel, voltage-gated, shaker-related subfamily. This member is one of the beta subunits, which are auxiliary proteins associating with functional Kv-alpha subunits. This member and the KCNA5 gene product assemble into a heteromultimeric A-type channel that inactivates completely and is significantly faster than other A-type Kv channels.

序列

Synthetic peptide located within the following region: RNLGKSGLRVSCLGLGTWVTFGSQISDETAEDVLTVAYEHGVNLFDTAEV

外形

Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

基本信息

NACRES NA.41

半岛bd体育手机客户端 性质

生物来源 rabbit
质量水平 100
偶联物 unconjugated
抗体形式 IgG fraction of antiserum
antibody product type primary antibodies
克隆 polyclonal
形式 buffered aqueous solution
分子量 44 kDa
species reactivity horse, guinea pig, dog, human, rat, bovine, rabbit
浓度 0.5 mg - 1 mg/mL
technique(s) immunohistochemistry: suitable
western blot: suitable
NCBI登记号 NP_004723
UniProt登记号 O43448
运输 wet ice
储存温度 ?20℃
Gene Information human ... KCNAB3(9196)

安全信息

储存分类代码 10 - Combustible liquids
WGK WGK 3
闪点(F) Not applicable
闪点(C) Not applicable

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