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Anti-GPR4 antibody produced in rabbit

品牌
Sigma-Aldrich
货号
SAB2900450
规格纯度
affinity isolated antibody
价格
8135.81 *本价格含增值税费
促销
服务
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  • 包邮
  • 增值税票
数量
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半岛bd体育手机客户端 名称:
Anti-GPR4 antibody produced in rabbit
G-protein coupled receptor 19
GPR4
Gpr6c
G-protein coupled receptor 4
G protein-coupled receptor 4
半岛bd体育手机客户端 介绍:

半岛bd体育手机客户端 说明

一般描述

Caspases mediate essential key proteolytic events in inflammatory cascades and the apoptotic cell death pathway. Caspase 12 is involved in the apoptosis triggered by a stress on the endoplasmic reticulum. Caspase-12 is co-localized to the ER with several proteins that are involved in Alzheimer′s disease including gamma-secretase presenilin and beta-amyloid precursor protein (APP). Caspase-12 mediates cytotoxicity induced by amyloid-beta. Caspase 12 activation results in cell death in the absence of the cytochrome c-dependent pathway. Recently caspase-12 has been suggested to affect signaling pathways linking some G-protein coupled receptors to alphaIIbbeta3 activation. Caspase-12 is ubiquitously expressed in mouse tissues.

免疫原

Synthetic 19 amino acid peptide from C-terminus of human GPR4. Percent identity with other species by BLAST analysis: Human, Gorilla, Gibbon, Monkey, Dog, Panda (100%); Mouse, Rat, Bovine, Bat, Pig (95%); Rabbit (89%).

特点和优势

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

外形

Supplied at 1 mg/ml
Solution in phosphate-buffered saline containing less than 0.1% sodium azide.

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

基本信息

NACRES NA.41

半岛bd体育手机客户端 性质

生物来源 rabbit
质量水平 100
偶联物 unconjugated
抗体形式 affinity isolated antibody
antibody product type primary antibodies
克隆 polyclonal
形式 buffered aqueous solution
species reactivity human
technique(s) immunohistochemistry: 24 μg/mL
UniProt登记号 P46093
运输 dry ice
储存温度 ?20℃
Gene Information human ... GPR4(2828)

安全信息

储存分类代码 12 - Non Combustible Liquids
闪点(F) Not applicable
闪点(C) Not applicable

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