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Anti-GEM antibody produced in rabbit

品牌
Sigma-Aldrich
货号
AV42226
规格纯度
IgG fraction of antiserum
价格
3311.54 *本价格含增值税费
促销
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数量
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半岛bd体育手机客户端 名称:
Anti-GEM antibody produced in rabbit
Anti-MGC26294
Anti-GTP binding protein overexpressed in skeletal muscle
Anti-KIR
半岛bd体育手机客户端 介绍:

半岛bd体育手机客户端 说明

一般描述

Gem/Kir, a Rad/Rem/Gem/Kir (RGK) GTPases family member, is a small GTP-binding protein involved in the regulation (inhibition) of high voltage-activated (HVA) Ca2+channels, such as the P/Q-Type Ca2+channels, that modulate neural, endocrine and muscle functions.

特异性

Anti-GEM polyclonal antibody reacts with bovine, human, mouse, rat, canine, and chicken Gem/Kir GTPase proteins.

免疫原

Synthetic peptide directed towards the C terminal region of human GEM

应用

Anti-GEM polyclonal antibody is used to tag Gem/Kir GTPase proteins for detection and quantitation by Western blotting and in cells and tissues by immunohistochemical (IHC) techniques. It is used as a probe to study the possible roles of Gem/Kir as inhibitors of high voltage-activated (HVA) Ca2+channels within neural, endocrine and muscle tissues.

生化/生理作用

GEM belongs to the RAD/GEM family of GTP-binding proteins. It is associated with the inner face of the plasma membrane and could play a role as a regulatory protein in receptor-mediated signal transduction.The protein encoded by this gene belongs to the RAD/GEM family of GTP-binding proteins. It is associated with the inner face of the plasma membrane and could play a role as a regulatory protein in receptor-mediated signal transduction. Alternative splicing occurs at this locus and two transcript variants encoding the same protein have been identified.

序列

Synthetic peptide located within the following region: ETSAAVQHNVKELFEGIVRQVRLRRDSKEKNERRLAYQKRKESMPRKARRFW

外形

Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

基本信息

NACRES NA.41

半岛bd体育手机客户端 性质

生物来源 rabbit
质量水平 100
偶联物 unconjugated
抗体形式 IgG fraction of antiserum
antibody product type primary antibodies
克隆 polyclonal
形式 buffered aqueous solution
分子量 33 kDa
species reactivity human, bovine, rabbit, rat, mouse, dog, horse, guinea pig
浓度 0.5 mg - 1 mg/mL
technique(s) immunohistochemistry: suitable
western blot: suitable
NCBI登记号 NP_859053
UniProt登记号 P55040
运输 wet ice
储存温度 ?20℃
Gene Information human ... GEM(2669)

安全信息

储存分类代码 12 - Non Combustible Liquids
WGK WGK 3
闪点(F) Not applicable
闪点(C) Not applicable

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