Anti-FICD antibody produced in rabbit

半岛bd体育手机客户端 说明

免疫原

Synthetic peptide directed towards the C terminal region of human FICD

应用

Anti-FICD antibody produced in rabbit is suitable for western blotting at a concentration of 0.25μg/mL. It is also useful for immunohistochemistry at a concentration of 4-8μg/mL.

生化/生理作用

FICD (FIC domain-containing protein) is a 458 amino acid containing single pass membrane protein. FICD facilitates the addition of adenosine 5′-monophosphate (AMP) to specific residues of target proteins. Hence, it mediates the AMP addition to RhoA, Rac and Cdc42 and inactivates the Rho GTPasesin vitro. Additionally, FICD arbitrates bacterial pathogenesis as well as eukaryotic posttranslational modification, which may facilitate in regulating key signaling events. In mammalian cells, Fic proteins injected by pathogenic bacteria stimulate the adenylylation of small GTPases that results in collapse of the actin cytoskeleton and cell death.

序列

Synthetic peptide located within the following region: GDVRPFIRFIAKCTETTLDTLLFATTEYSVALPEAQPNHSGFKETLPVKP

外形

Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

基本信息

NACRES

NA.41

半岛bd体育手机客户端 性质

生物来源	rabbit
质量水平	100
偶联物	unconjugated
抗体形式	affinity isolated antibody
antibody product type	primary antibodies
克隆	polyclonal
形式	buffered aqueous solution
分子量	52 kDa
species reactivity	bovine, mouse, pig, dog, human, horse, rat
浓度	0.5 mg - 1 mg/mL
technique(s)	immunohistochemistry: suitable western blot: suitable
NCBI登记号	NP_009007
UniProt登记号	Q9BVA6
运输	wet ice
储存温度	?20℃
Gene Information	human ... FICD(11153)

安全信息

储存分类代码	12 - Non Combustible Liquids
WGK	WGK 3
闪点(F)	Not applicable
闪点(C)	Not applicable