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Anti-FBXW7 antibody, Rabbit monoclonal

品牌
Sigma-Aldrich
货号
SAB5500104
规格纯度
clone SP237, recombinant, expressed in proprietary host, affinity isolated antibody
价格
4330.86 *本价格含增值税费
促销
服务
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数量
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半岛bd体育手机客户端 名称:
Anti-FBXW7 antibody, Rabbit monoclonal
半岛bd体育手机客户端 介绍:

半岛bd体育手机客户端 说明

一般描述

F-box/WD repeat-containing protein 7 (Fbxw7) is part of an ubiquitin-protein ligase complex. The complex ubiquitinates and degrades several important oncogenes such as mTOR, MYC, AURKA, JUN, and NOTCH1. Fbxw7 cooperates with PTEN for tumor suppression and is widely expressed in many normal tissues. The loss of fbxw7 is associated with malignant progression in a variety of tumors, including carcinoma of colorectum, lung, stomach, bile duct, endometrium, pancreas, breast and glioblastoma.

免疫原

Synthetic peptide derived from the internal region of human FBXW7 protein.

特点和优势

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

外形

0.1 ml rabbit monoclonal antibody purified by protein A/G in PBS/1% BSA buffer pH 7.6 with less than 0.1% sodium azide.

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

基本信息

NACRES NA.41

半岛bd体育手机客户端 性质

生物来源 rabbit
质量水平 100
重组 expressed in proprietary host
偶联物 unconjugated
抗体形式 affinity isolated antibody
antibody product type primary antibodies
克隆 SP237, monoclonal
species reactivity human (tested)
species reactivity (predicted by homology) rat, mouse
technique(s) flow cytometry: 1:400
immunohistochemistry: 1:100
同位素/亚型 IgG
UniProt登记号 Q969H0
运输 wet ice
储存温度 2-8℃
Gene Information human ... FBXW7(55294)

安全信息

储存分类代码 12 - Non Combustible Liquids
WGK WGK 2
闪点(F) Not applicable
闪点(C) Not applicable

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