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位置: 首页> 品牌> Sigma-Aldrich> Anti-FBXW2 antibody produced in rabbit

Anti-FBXW2 antibody produced in rabbit

品牌
Sigma-Aldrich
货号
SAB2100800
规格纯度
affinity isolated antibody
价格
6305.78 *本价格含增值税费
促销
服务
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数量
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半岛bd体育手机客户端 名称:
Anti-FBXW2 antibody produced in rabbit
Anti-MGC117371
Anti-FBW2
Anti-F-box and WD repeat domain containing 2
Anti-Fwd2
Anti-Md6
半岛bd体育手机客户端 介绍:

半岛bd体育手机客户端 说明

免疫原

Synthetic peptide directed towards the middle region of human FBXW2

生化/生理作用

F-box proteins are an expanding family of eukaryotic proteins characterized by an approximately 40 amino acid motif, the F box. Some F-box proteins have been shown to be critical for the ubiquitin-mediated degradation of cellular regulatory proteins. In fact, F-box proteins are one of the four subunits of ubiquitin protein ligases, called SCFs. SCF ligases bring ubiquitin conjugating enzymes to substrates that are specifically recruited by the different F-box proteins. Mammalian F-box proteins are classified into three groups based on the presence of either WD-40 repeats, leucine-rich repeats, or the presence or absence of other protein-protein interacting domains. FBXW2 is the second identified member of the F-box family and contains multiple WD-40 repeats.F-box proteins are an expanding family of eukaryotic proteins characterized by an approximately 40 amino acid motif, the F box. Some F-box proteins have been shown to be critical for the ubiquitin-mediated degradation of cellular regulatory proteins. In fact, F-box proteins are one of the four subunits of ubiquitin protein ligases, called SCFs. SCF ligases bring ubiquitin conjugating enzymes to substrates that are specifically recruited by the different F-box proteins. Mammalian F-box proteins are classified into three groups based on the presence of either WD-40 repeats, leucine-rich repeats, or the presence or absence of other protein-protein interacting domains. This gene encodes the second identified member of the F-box gene family and contains multiple WD-40 repeats.

序列

Synthetic peptide located within the following region: SLISRWPLPEYRKSKRGSSFLAGEASWLNGLDGHNDTGLVFATSMPDHSI

外形

Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

基本信息

NACRES NA.41

半岛bd体育手机客户端 性质

生物来源 rabbit
质量水平 100
偶联物 unconjugated
抗体形式 affinity isolated antibody
antibody product type primary antibodies
克隆 polyclonal
形式 buffered aqueous solution
分子量 51 kDa
species reactivity horse, human, guinea pig, mouse, bovine, rat, dog, rabbit
浓度 0.5 mg - 1 mg/mL
technique(s) western blot: suitable
UniProt登记号 Q9UKT8
运输 wet ice
储存温度 ?20℃
Gene Information human ... FBXW2(26190)

安全信息

储存分类代码 12 - Non Combustible Liquids
WGK WGK 3
闪点(F) Not applicable
闪点(C) Not applicable

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