半岛bd体育手机客户端 说明
免疫原
Synthetic peptide directed towards the C terminal region of human CUL1
应用
Anti-CUL1 antibody produced in rabbit is suitable for western blotting at a concentration of 1.25 μg/ml.
生化/生理作用
Cullin1, a cullin-based ubiquitin ligase, is a scaffold protein that has important role in embryonic development. It promotes the invasion of human trophoblast progenitor cells by increasing the expression of MMP-9 and decreasing TIMP-1 and TIMP-2. In collaboration with Rictor protein, CUL1 promotes the ubiquitination of SGK1 that is important in maintaining cell homeostasis.
序列
Synthetic peptide located within the following region: HQQLLGEVLTQLSSRFKPRVPVIKKCIDILIEKEYLERVDGEKDTYSYLA
外形
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
基本信息
| MDL编号 | MFCD02096156 |
| NACRES | NA.41 |
半岛bd体育手机客户端 性质
| 生物来源 | rabbit |
| 质量水平 | 100 |
| 偶联物 | unconjugated |
| 抗体形式 | IgG fraction of antiserum |
| antibody product type | primary antibodies |
| 克隆 | polyclonal |
| 形式 | buffered aqueous solution |
| 分子量 | 90 kDa |
| species reactivity | bovine, mouse, dog, rat, human |
| 浓度 | 0.5 mg - 1 mg/mL |
| technique(s) | western blot: suitable |
| NCBI登记号 | NP_003583 |
| UniProt登记号 | Q13616 |
| 运输 | wet ice |
| 储存温度 | −20℃ |
| Gene Information | human ... CUL1(8454) |
安全信息
| 储存分类代码 | 12 - Non Combustible Liquids |
| WGK | WGK 3 |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
Sigma-Aldrich
m.cnreagent.com
