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Anti-CRSP6 antibody produced in rabbit

品牌
Sigma-Aldrich
货号
AV34192
规格纯度
affinity isolated antibody
价格
6305.78 *本价格含增值税费
促销
服务
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  • 包邮
  • 增值税票
数量
- +
半岛bd体育手机客户端 名称:
Anti-CRSP6 antibody produced in rabbit
Anti-Cofactor required for Sp1 transcriptional activation, subunit 6, 77 kDa
半岛bd体育手机客户端 介绍:

半岛bd体育手机客户端 说明

一般描述

CRSP6 (MED17) is a subunit of the CRSP (cofactor required for SP1 activation) complex which interacts with TFIID and SP1 to mediate transcriptional initiation. MED17 mutations have been linked to infantile cerebral and cerebellar atrophy.
Rabbit Anti-CRSP6 antibody recognizes chicken, rat, mouse, human, canine, and bovine CRSP6.

免疫原

Synthetic peptide directed towards the N terminal region of human CRSP6

应用

Rabbit Anti-CRSP6 antibody can be used for western blot applications at 0.5 μg/ml. It can also be used for IHC of paraffin-embedded tissues at 4-8 μg/ml.

生化/生理作用

The activation of gene transcription is a multistep process that is triggered by factors that recognize transcriptional enhancer sites in DNA. These factors work with co-activators to direct transcriptional initiation by the RNA polymerase II apparatus. The protein encoded by CRSP6 is a subunit of the CRSP (cofactor required for SP1 activation) complex, which, along with TFIID, is required for efficient activation by SP1. This protein is also a component of other multisubunit complexes e.g. thyroid hormone receptor-(TR-) associated proteins which interact with TR and facilitate TR function on DNA templates in conjunction with initiation factors and cofactors.

序列

Synthetic peptide located within the following region: AAQILLKGAERLTKSVTENQENKLQRDFNSELLRLRQHWKLRKVGDKILG

外形

Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

基本信息

NACRES NA.41

半岛bd体育手机客户端 性质

生物来源 rabbit
质量水平 100
偶联物 unconjugated
抗体形式 affinity isolated antibody
antibody product type primary antibodies
克隆 polyclonal
形式 buffered aqueous solution
分子量 73 kDa
species reactivity guinea pig, rat, bovine, dog, rabbit, horse, human
浓度 0.5 mg - 1 mg/mL
technique(s) ChIP: suitable
immunohistochemistry: suitable
western blot: suitable
NCBI登记号 NP_004259
UniProt登记号 Q9NVC6
运输 wet ice
储存温度 ?20℃
Gene Information human ... CRSP6(9440)

安全信息

储存分类代码 12 - Non Combustible Liquids
WGK WGK 3
闪点(F) Not applicable
闪点(C) Not applicable

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