Anti-CDK4 (AB2) antibody produced in rabbit

半岛bd体育手机客户端 说明

免疫原

The immunogen for anti-CDK4 antibody: synthetic peptide derected towards the C terminal of human CDK4

应用

Anti-CDK4 (AB2) antibody produced in rabbit is suitable for western blotting at a concentration of 1 μg/ml.

生化/生理作用

CDK4 forms a complex with cyclin D1 and regulates cell proliferation during the G1 phase. It also binds with human p16 and inhibits the activity of the CDK4/cyclin D complex in cells that lack retinoblastoma protein. CDK4 forms a complex with pRB and E2F1 proteins that modulate the secretion of insulin by pancreatic β-cells.

序列

Synthetic peptide located within the following region: PRPVQSVVPEMEESGAQLLLEMLTFNPHKRISAFRALQHSYLHKDEGNPE

外形

Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

基本信息

MDL编号	MFCD00282839
NACRES	NA.41

半岛bd体育手机客户端 性质

生物来源	rabbit
质量水平	100
偶联物	unconjugated
抗体形式	IgG fraction of antiserum
antibody product type	primary antibodies
克隆	polyclonal
形式	buffered aqueous solution
分子量	34 kDa
species reactivity	rabbit, canine, rat, human, pig
浓度	0.5 mg - 1 mg/mL
technique(s)	western blot: suitable
NCBI登记号	NP_000066
UniProt登记号	P11802
运输	wet ice
储存温度	?20℃
Gene Information	human ... CDK4(1019)

安全信息

储存分类代码	12 - Non Combustible Liquids
WGK	WGK 3
闪点(F)	Not applicable
闪点(C)	Not applicable