Anti-C5ORF39 antibody produced in rabbit

半岛bd体育手机客户端 说明

免疫原

Synthetic peptide directed towards the N terminal region of human C5orf39

应用

Anti-C5ORF39 antibody produced in rabbit is suitable for western blotting at a concentration of 1μg/mL.

生化/生理作用

C5ORF39 or AX2R (annexin A2 receptor) gene encodes a cell surface receptor for annexin II. It is predominantly expressed in lymphocytes, in both resting CD4⁺and CD8⁺T-cell. AX2R is located in cytoplasm where it binds to and stimulates pro-caspase-8 followed by caspase-3/7. Hence, AX2R induces apoptosis independent of annexin II and FADD. Annexin II binds to AXIIR and enhances the multiple myeloma cell adhesion and growth in the bone marrow microenvironment. Additionally, annexin II and its receptor AXIIR regulates adhesion, migration, homing, and growth of prostate cancer.

序列

Synthetic peptide located within the following region: EQHFLGCVKRAWDSAEVAPEPQPPPIVSSEDRGPWPLPLYPVLGEYSLDS

外形

Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

基本信息

NACRES

NA.41

半岛bd体育手机客户端 性质

生物来源	rabbit
质量水平	100
偶联物	unconjugated
抗体形式	affinity isolated antibody
antibody product type	primary antibodies
克隆	polyclonal
形式	buffered aqueous solution
分子量	22 kDa
species reactivity	human
浓度	0.5 mg - 1 mg/mL
technique(s)	western blot: suitable
NCBI登记号	NP_001014301
UniProt登记号	Q3ZCQ2
运输	wet ice
储存温度	?20℃
Gene Information	human ... C5orf39(389289)

安全信息

储存分类代码	12 - Non Combustible Liquids
WGK	WGK 3
闪点(F)	Not applicable
闪点(C)	Not applicable