ANTI-ARPC1A (C-TERM) antibody produced in rabbit

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应用

ANTI-ARPC1A (C-TERM) antibody produced in rabbit is suitable for flow cytometry (1:10-1:50), immunohistochemistry (1:50-1:100), indirect immunofluorescence (1:10-1:50) and western blot (1:250-1:500).

生化/生理作用

ARPC1A (actin related protein 2/3 complex, subunit 1A, 41kDa) encodes p41 subunit of the Arp2/3 protein complex. It is a vital regulator component of actin polymerization complex, named Arp2/3 complex. The complex interacts with the exocyst component Exo70 to regulate cell migration as well as the cytoskeleton and membrane trafficking during cell migration. During actin polymerization, it initiates actin assembly on the surface of the motile intracellular pathogenListeria monocytogenes. Later, it nucleates and cross-links with actin filamentsin vitro. Finally, it localizes with dynamic actin-rich spots of mammalian cells, suggesting a role in protrusion.

外形

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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