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位置: 首页> 品牌> Sigma-Aldrich> Rabbit anti-PKM2 Antibody, Affinity Purified

Rabbit anti-PKM2 Antibody, Affinity Purified

品牌
Sigma-Aldrich
货号
PLA0286
规格纯度
Powered by Bethyl Laboratories, Inc.
价格
5699.93 *本价格含增值税费
促销
服务
  • 原厂保证
  • 包邮
  • 增值税票
数量
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半岛bd体育手机客户端 名称:
Rabbit anti-PKM2 Antibody, Affinity Purified
PK
muscle type
PK3
OIP3
Cytosolic thyroid hormone-binding protein
Pyruvate kinase muscle isozyme
thyroid hormone-binding protein
tumor M2-PK
HEL-S-30
OPA-interacting protein 3
OIP-3
CTHBP
TCB
p58
cytosolic
THBP1
Pyruvate kinase 2/3
Pyruvate kinase isozymes M1/M2
epididymis secretory protein Li 30
thyroid hormone-binding protein 1
PKM2
半岛bd体育手机客户端 介绍:

半岛bd体育手机客户端 说明

免疫原

The epitope recognized by PLA0286 maps to a region between residue 481 and 531 of human Pyruvate Kinase Isozymes M1/M2 using the numbering given in entry NP_002645.3 (GeneID 5315).

外形

Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09% Sodium Azide

其他说明

Pyruvate Kinase M2 (PKM2) is a glycolytic enzyme that catalyzes the transfer of a phosphoryl group from phosphoenolpyruvate (PEP) to ADP, generating ATP. The ratio between the highly active tetrameric form and nearly inactive dimeric form determines whether glucose carbons are channeled to biosynthetic processes or used for glycolytic ATP production. The transition between the 2 forms contributes to the control of glycolysis and is important for tumor cell proliferation and survival. PKM2 also stimulates POU5F1-mediated transcriptional activation, and plays a general role in caspase independent cell death of tumor cells [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/ P14618].

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

基本信息

NACRES NA.41

半岛bd体育手机客户端 性质

生物来源 rabbit
质量水平 100
抗体形式 affinity purified immunoglobulin
antibody product type primary antibodies
等级 Powered by Bethyl Laboratories, Inc.
species reactivity mouse, human
technique(s) immunohistochemistry: 1:1,000-1:5,000
immunoprecipitation (IP): 2- 10 μg/mg
western blot: 1:2,000- 1:10,000
登记号 NP_002645.3
运输 wet ice
储存温度 2-8℃
Gene Information rabbit ... PKM2(5315)

安全信息

储存分类代码 12 - Non Combustible Liquids
WGK nwg
闪点(F) Not applicable
闪点(C) Not applicable

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