Rabbit anti-p73 Antibody, Affinity Purified

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免疫原

The epitope recognized by PLA0040 maps to a region between residues 1 and 62 of human tumor protein p73 using the numbering given in Swiss-Prot entry O15350 (GeneID 7161).

外形

Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09% Sodium Azide

其他说明

p73 is a p53-related protein and a member of the family of transcription factors which include p53, p63 and p73. Although structurally and functionally related, it appears that the members of this family possess their own unique functions. No human genetic disorders have been linked to germ line mutations of p73; however, loss of heterozygosity has been associated with some cancers although the incidence is rare. Generally speaking, p73 appears to play an important role in gene transactivation and growth suppression. P73 participates in the apoptotic response to DNA damage and may function in connection with p53.

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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