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Monoclonal Anti-LIN7A antibody produced in mouse

品牌
Sigma-Aldrich
货号
SAB2702318
规格纯度
clone GT377, affinity isolated antibody
价格
6575.61 *本价格含增值税费
促销
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数量
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半岛bd体育手机客户端 名称:
Monoclonal Anti-LIN7A antibody produced in mouse
MALS-1
LIN7
TIP-33
LIN-7A
半岛bd体育手机客户端 介绍:

半岛bd体育手机客户端 说明

免疫原

Recombinant protein encompassing a sequence within the center region of human LIN7A.

应用

Suggested starting dilutions are as follows: ICC/IF: 1:100-1:1000, WB: 1:500-1:3000. Not yet tested in other applications. Optimal working dilutions should be determined experimentally by the end user.

生化/生理作用

Plays a role in establishing and maintaining the asymmetric distribution of channels and receptors at the plasma membrane of polarized cells. Forms membrane-associated multiprotein complexes that may regulate delivery and recycling of proteins to the correct membrane domains. The tripartite complex composed of LIN7 (LIN7A, LIN7B or LIN7C), CASK and APBA1 may have the potential to couple synaptic vesicle exocytosis to cell adhesion in brain. Ensures the proper localization of GRIN2B (subunit 2B of the NMDA receptor) to neuronal postsynaptic density and may function in localizing synaptic vesicles at synapses where it is recruited by beta-catenin and cadherin. Required to localize Kir2 channels, GABA transporter (SLC6A12) and EGFR/ERBB1, ERBB2, ERBB3 and ERBB4 to the basolateral membrane of epithelial cells.

特点和优势

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

其他说明

Purification: Affinity purified by Protein G

外形

Phosphate-buffered saline, no preservative added.

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

基本信息

NACRES NA.41

半岛bd体育手机客户端 性质

质量水平 100
生物来源 mouse
偶联物 unconjugated
抗体形式 affinity isolated antibody
antibody product type primary antibodies
克隆 GT377, monoclonal
形式 buffered aqueous solution
分子量 26kDa
species reactivity human
浓度 1mg/mL
technique(s) indirect immunofluorescence: suitable
western blot: 500-3000
同位素/亚型 IgG2b
UniProt登记号 O14910
运输 wet ice
储存温度 ?20℃
Gene Information human ... LIN7A(8825)

安全信息

储存分类代码 12 - Non Combustible Liquids
WGK WGK 1
闪点(F) Not applicable
闪点(C) Not applicable

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