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位置: 首页> 品牌> Sigma-Aldrich> Monoclonal Anti-GRHL3 antibody produced in mouse

Monoclonal Anti-GRHL3 antibody produced in mouse

品牌
Sigma-Aldrich
货号
WH0057822M1
规格纯度
clone 3C5, purified immunoglobulin, buffered aqueous solution
价格
4474.51 *本价格含增值税费
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数量
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半岛bd体育手机客户端 名称:
Monoclonal Anti-GRHL3 antibody produced in mouse
Anti-MGC46624
Anti-grainyhead-like 3 (Drosophila)
Anti-TFCP2L4
Anti-SOM
半岛bd体育手机客户端 介绍:

半岛bd体育手机客户端 说明

一般描述

Grainyhead-like 3 (GRHL3), also known as GET1, is encoded by the gene mapped to human chromosome 1p36.11. GRHL3 is one of the mammalian homologues of Grh gene.

免疫原

GRHL3 (NP_067003, 101 a.a. ~ 200 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Sequence
YETDLTPLESPTHLMKFLTENVSGTPEYPDLLKKNNLMSLEGALPTPGKAAPLPAGPSKLEAGSVDSYLLPTTDMYDNGSLNSLFESIHGVPPTQRWQPD

生化/生理作用

Grainyhead-like 3 (GRHL3) stimulates gene expression programs involved in various cellular processes, such as cell adhesion, lipid production, cornified envelope formation and protein crosslinking. In addition, it also facilitates keratinocyte migration during eyelid closure and wound healing. Missense mutation in the gene is associated with the development of nonsyndromic cleft palate. In addition, variation in the gene also leads to Van der Woude syndrome (VWS). The protein expression can be used as a diagnostic factor for germinal center B cell (GCB) /non-GCB of diffuse large B cell lymphoma.

外形

Solution in phosphate buffered saline, pH 7.4

法律信息

GenBank is a registered trademark of United States Department of Health and Human Services

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

基本信息

NACRES NA.41

半岛bd体育手机客户端 性质

质量水平 100
生物来源 mouse
偶联物 unconjugated
抗体形式 purified immunoglobulin
antibody product type primary antibodies
克隆 3C5, monoclonal
形式 buffered aqueous solution
species reactivity human
technique(s) indirect ELISA: suitable
western blot: 1-5 μg/mL
同位素/亚型 IgG2aκ
GenBank?accession no. NM_021180
UniProt登记号 Q8TE85
运输 dry ice
储存温度 ?20℃
Gene Information human ... GRHL3(57822)

安全信息

储存分类代码 12 - Non Combustible Liquids
WGK nwg
闪点(F) Not applicable
闪点(C) Not applicable
个人防护装备 Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)

Sigma-Aldrich

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