半岛bd体育手机客户端 说明
免疫原
Amino acids 1-153 of human ER-§ expressed in E. coli.
应用
For WB: Use at a concentration of 1 - 5 μg/mL. Predicted molecular weight: 59 kDa.For ICC/IF:Use at an dependent assay. For ChIP:Use at an dependent assay. Optimal dilutions/concentrations should be determined by the researcher.
生化/生理作用
The human ER-beta is a newly discovered estrogen receptor initially cloned and characterized from testis. The size and structure of ER-beta is very similar to ER-alpha with the ligand and DNA binding domains being highly conserved, while the amino terminus which serves as their transactivation domain has diverged significantly. Similar in function to ER-alpha ER-beta binds to estrogen with a high affinity and regulates estrogen specific gene activation through direct interaction with estrogen response elements (ERE′s).
特点和优势
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外形
Phosphate-buffered saline, pH 7.4, containing no preservatives
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
基本信息
| NACRES | NA.41 |
半岛bd体育手机客户端 性质
| 质量水平 | 100 |
| 生物来源 | mouse |
| 偶联物 | unconjugated |
| 抗体形式 | purified immunoglobulin |
| antibody product type | primary antibodies |
| 克隆 | 6A12 monoclonal |
| 形式 | liquid |
| 分子量 | 58-60 kDa |
| species reactivity | human |
| 浓度 | 1 mg/mL |
| technique(s) | ChIP: suitable immunocytochemistry: suitable immunofluorescence: suitable immunohistochemistry: suitable immunoprecipitation (IP): suitable western blot: 1-5 μg/mL |
| 同位素/亚型 | IgG2b |
| UniProt登记号 | Q92731 |
| 运输 | wet ice |
| 储存温度 | ?20℃ |
| Gene Information | human ... ESR2(2100) |
安全信息
| 储存分类代码 | 12 - Non Combustible Liquids |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
Sigma-Aldrich
m.cnreagent.com
