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位置: 首页> 品牌> Sigma-Aldrich> Monoclonal Anti-CYP2A6 antibody produced in mouse

Monoclonal Anti-CYP2A6 antibody produced in mouse

品牌
Sigma-Aldrich
货号
SAB1402744
规格纯度
clone 3B11, purified immunoglobulin, buffered aqueous solution
价格
4618.16 *本价格含增值税费
促销
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数量
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半岛bd体育手机客户端 名称:
Monoclonal Anti-CYP2A6 antibody produced in mouse
CPA6
P450PB
P450C2A
CYP2A3
CYP2A
半岛bd体育手机客户端 介绍:

半岛bd体育手机客户端 说明

一般描述

This gene, CYP2A6, encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and its expression is induced by phenobarbital. The enzyme is known to hydroxylate coumarin, and also metabolizes nicotine, aflatoxin B1, nitrosamines, and some pharmaceuticals. Individuals with certain allelic variants are said to have a poor metabolizer phenotype, meaning they do not efficiently metabolize coumarin or nicotine. This gene is part of a large cluster of cytochrome P450 genes from the CYP2A, CYP2B and CYP2F subfamilies on chromosome 19q. The gene was formerly referred to as CYP2A3; however, it has been renamed CYP2A6. (provided by RefSeq)

免疫原

CYP2A6 (AAH28215, 395 a.a. ~ 494 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Sequence
LGSVLRDPSFFSNPQDFNPQHFLNEKGQFKKSDAFVPFSIGKRNCFGEGLARMELFLFFTTVMQNFRLKSSQSPKDIDVSPKHVGFATIPRNYTMSFLPR

外形

Solution in phosphate buffered saline, pH 7.4

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

基本信息

NACRES NA.41

半岛bd体育手机客户端 性质

质量水平 100
生物来源 mouse
偶联物 unconjugated
抗体形式 purified immunoglobulin
antibody product type primary antibodies
克隆 3B11, monoclonal
形式 buffered aqueous solution
分子量 antigen ~37.11 kDa
species reactivity human
technique(s) capture ELISA: suitable
indirect ELISA: suitable
western blot: 1-5 μg/mL
同位素/亚型 IgG2aκ
NCBI登记号 NG_000008
UniProt登记号 P11509
运输 dry ice
储存温度 ?20℃
Gene Information human ... CYP2A6(1548)

安全信息

储存分类代码 13 - Non Combustible Solids
WGK WGK 1
闪点(F) Not applicable
闪点(C) Not applicable

Sigma-Aldrich

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