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位置: 首页> 品牌> Sigma-Aldrich> Monoclonal Anti-C19orf62 antibody produced in mouse

Monoclonal Anti-C19orf62 antibody produced in mouse

品牌
Sigma-Aldrich
货号
SAB2702274
规格纯度
clone GT1251, affinity isolated antibody
价格
6575.61 *本价格含增值税费
促销
服务
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数量
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半岛bd体育手机客户端 名称:
Monoclonal Anti-C19orf62 antibody produced in mouse
C19orf62
NBA1
HSPC142
MERIT40
半岛bd体育手机客户端 介绍:

半岛bd体育手机客户端 说明

免疫原

Recombinant protein encompassing a sequence within the N-terminus region of human C19orf62.

应用

Suggested starting dilutions are as follows: ICC/IF: 1:100-1:1000, WB: 1:500-1:3000. Not yet tested in other applications. Optimal working dilutions should be determined experimentally by the end user.

生化/生理作用

Component of the BRCA1-A complex, a complex that specifically recognizes ′Lys-63′-linked ubiquitinated histones H2A and H2AX at DNA lesions sites, leading to target the BRCA1-BARD1 heterodimer to sites of DNA damage at double-strand breaks (DSBs). The BRCA1-A complex also possesses deubiquitinase activity that specifically removes ′Lys-63′-linked ubiquitin on histones H2A and H2AX. In the BRCA1-A complex, it is required for the complex integrity and its localization at DSBs. Probably also plays a role as a component of the BRISC complex, a multiprotein complex that specifically cleaves ′Lys-63′-linked ubiquitin. In these 2 complexes, it is probably required to maintain the stability of BRE/BRCC45 and help the ′Lys-63′-linked deubiquitinase activity mediated by BRCC3/BRCC36. component.

特点和优势

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

其他说明

Purification: Affinity purified by Protein G

外形

Phosphate-buffered saline, no preservative added.

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

基本信息

NACRES NA.41

半岛bd体育手机客户端 性质

质量水平 100
生物来源 mouse
偶联物 unconjugated
抗体形式 affinity isolated antibody
antibody product type primary antibodies
克隆 GT1251, monoclonal
形式 buffered aqueous solution
species reactivity human
浓度 1mg/mL
technique(s) indirect immunofluorescence: suitable
western blot: 500-3000
同位素/亚型 IgG2a
UniProt登记号 Q9NWV8
运输 wet ice
储存温度 ?20℃
Gene Information human ... BABAM1(29086)

安全信息

储存分类代码 12 - Non Combustible Liquids
WGK WGK 1
闪点(F) Not applicable
闪点(C) Not applicable

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