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位置:首页 > 品牌 > Sigma-Aldrich > Monoclonal Anti-Anti-AKT3 antibody produced in mouse

Monoclonal Anti-Anti-AKT3 antibody produced in mouse

品牌
Sigma-Aldrich
货号
SAB3701467
规格纯度
clone 25F6.F6.D8, purified immunoglobulin
价格
6082.18 *本价格含增值税费
促销
服务
  • 原厂保证
  • 包邮
  • 增值税票
数量
-+
半岛bd体育手机客户端 名称:
Monoclonal Anti-Anti-AKT3 antibody produced in mouse
Anti-TRPC6
Anti-PKBGAMMA Antibody
Anti-AKT-3
Anti-PKB gamma antibody
Anti-PKB antibody
半岛bd体育手机客户端 介绍:

半岛bd体育手机客户端 说明

一般描述

AKT serine/threonine kinase 3 (AKT3) is part of the protein kinase B family. It has a kinase domain, a pleckstrin homology domain and a regulatory domain. The protein consists of 479 amino acids and the gene encoding it is localized on human chromosome 1q44.

特异性

Anti-AKT3 antibody is directed against human AKT3. The antibody detects both unphosphorylated and phosphorylated forms of the protein. Anti-AKT3 antibody was purified from ascites by Protein A chromatography. Cross reactivity with AKT3 from other species has not been determined, however, the sequence of the immunogen shows 100% identity to human, mouse, and rat, therefore, cross reactivity is expected. Cross-reactivity with AKT2 and AKT has not been determined.

免疫原

Synthetic peptide corresponding to internal residues of human AKT3 protein.

生化/生理作用

AKT serine/threonine kinase 3 (AKT3) has a role in DNA repair and brain development. In mouse model, it modulates the expression of estrogen receptor α, Erb-B2 receptor tyrosine kinase 2 and Erb-B2 receptor tyrosine kinase 3 in breast cancer cells. AKT3 has been shown to stimulate the growth of triple-negative breast cancer.

特点和优势

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

外形

Supplied in 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2 with 0.01% (w/v) Sodium Azide

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

半岛bd体育手机客户端 性质

质量水平100
生物来源mouse
偶联物unconjugated
抗体形式purified immunoglobulin
antibody product typeprimary antibodies
克隆25F6.F6.D8, monoclonal
形式buffered aqueous solution
species reactivityhuman
technique(s)ELISA: suitable
immunohistochemistry: suitable
western blot: suitable
同位素/亚型IgG1κ
UniProt登记号Q9Y243
运输dry ice
储存温度−20℃
Gene Informationhuman ... AKT3(10000)

安全信息

储存分类代码12 - Non Combustible Liquids
WGKnwg
闪点(F)Not applicable
闪点(C)Not applicable

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