t-Boc-N-amido-PEG_2-CH₂CO₂H

半岛bd体育手机客户端 说明

应用

t-Boc-N-amido-PEG₂-CH₂CO₂H is a heterobifunctional, PEGylated crosslinker featuring a Boc-protected amine at one end and a carboxyl group at the other. The hydrophillic PEG linker facilitates solubility in biological applications. t-Boc-N-amido-PEG₂-CH₂CO₂H can be used for bioconjugation or as a building block for synthesis of small molecules, conjugates of small molecules and/or biomolecules, or other tool compounds for chemical biology and medicinal chemistry that require ligation. Examples of applications include its synthetic incorporation into antibody-drug conjugates or proteolysis-targeting chimeras (PROTAC^?molecules) for targeted protein degradation.
This is a crosslinker with at-Boc protected amine on one end and a carboxyl group on the other end. The compound contains two PEG units to help improve solubility.

法律信息

PROTAC is a registered trademark of Arvinas Operations, Inc., and is used under license

基本信息

经验(实验)分子式	C11H21NO6
分子量	263.29
MDL编号	MFCD17019374

半岛bd体育手机客户端 性质

测定	≥95%
形式	liquid
密度	1.15 g/cm3(lit.)
储存温度	?20℃
SMILES string	OC(COCCOCCNC(OC(C)(C)C)=O)=O

安全信息

储存分类代码	12 - Non Combustible Liquids
WGK	WGK 3