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SILuTMProt IFNG Interferon Gamma human

品牌
Sigma-Aldrich
货号
MSST0039
规格纯度
recombinant, expressed in HEK 293 cells, SIL MS Protein Standard,13C and15N-labeled
价格
9134.92 *本价格含增值税费
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数量
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半岛bd体育手机客户端 名称:
SILu TMProt IFNG Interferon Gamma human
Immune interferon
IFN-gamma
IFNγ
Immuneinterferon
半岛bd体育手机客户端 介绍:

半岛bd体育手机客户端 说明

一般描述

Interferon gamma (IFNγ) is a dimerized soluble cytokine that is the only member of the type II class of interferons. IFNγ is secreted by T helper cells (specifically, Th1 cells), cytotoxic T cells (TC cells) and Natural killer (NK) cells. When combined with other inflammatory cytokines, evaluating the levels of IFNγ can be used as a diagnostic tool in patients with breast cancer or benign prostatic hyperplasia. A recent study evaluated the effect of a cancer vaccine given to patients with colorectal cancer, on the levels of plasma pro-inflammatory cytokines (including IFN-γ). The study concluded that patients achieving stable disease showed increasing levels of plasma inflammatory cytokines.

免疫原

QDPYVKEAENLKKYFNAGHSDVADNGTLFLGILKNWKEESDRKIMQSQIVSFYFKLFKNFKDDQSIQKSVETIKEDMNVKFFNSNKKKRDDFEKLTNYSVTDLNVQRKAIHELIQVMAELSPAAKTGKRKRSQMLFRG

生化/生理作用

SILu?Prot IFNG is a recombinant, stable isotope-labeled human IFNG which incorporates [13C6,15N4]-Arginine and [13C6,15N2]-Lysine. Expressed in human 293 cells, it is designed to be used as an internal standard for bioanalysis of IFNG in mass-spectrometry. SILu Prot IFNG is a homodimer consisting of 138 amino acids, with a calculated molecular mass of 17 kDa.

外形

Supplied as a lyophilized powder containing phosphate buffered saline.

法律信息

This product is licensed under U.S. Patent No. 7,396,688 and foreign counterparts from E. I. du Pont de Nemours and Company. The purchase of this product conveys to the buyer the nontransferable right to use the purchased amount of the product for research and development only, including services for a third party for consideration. The buyer cannot sell or otherwise transfer this product, its components or materials made using this product or its components to a third party. Information about licenses for excluded uses is available from: E. I. du Pont de Nemours and Company; Attn: Associate Director, Commercial Development; DuPont Experimental Station E268; 200 Powdermill Rd.; Wilmington, DE 19803; 1-877-881-9787 (voice), 1-302-695-1437 (fax), licensing@dupont.com.
SILu is a trademark of sigma-aldrich Co. LLC

基本信息

NACRES NA.12

半岛bd体育手机客户端 性质

质量水平 200
生物来源 human
重组 expressed in HEK 293 cells
测定 ≥98% (SDS-PAGE)
形式 lyophilized powder
效能 ≥98% Heavy amino acids incorporation efficiency by MS
分子量 calculated mol wt 17 kDa
technique(s) mass spectrometry (MS): suitable
适用性 suitable for mass spectrometry (standard)
UniProt登记号 P01579
储存温度 ?20℃
Gene Information human ... IFNG(3458)

安全信息

储存分类代码 11 - Combustible Solids
WGK WGK 2
闪点(F) Not applicable
闪点(C) Not applicable

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