SILu^TMProt APOA2 Apolipoprotein A-II human

半岛bd体育手机客户端 说明

一般描述

Apolipoprotein A-II (ApoA-II) occurs in plasma as a dimer of two 77-amino acid chains linked by a disulfide bridge. After apoA-I, it is the second major protein component of HDL, accounting for approximately 20% of HDL total protein. ApoA-II is thought to play an important role in triglyceride metabolism both from animal and human studies. 3 Recent findings attribute apoA-II to inhibitory effects on lipoprotein lipase-mediated hydrolysis of triglyceride-rich particles. Additional associations of apoA-II have been reported for a variety of protein factors including hepatic lipase (HL), lipoprotein lipase (LPL), endothelial lipase, CETP, PLTP, and LCAT.

免疫原

QAKEPCVESLVSQYFQTVTDYGKDLMEKVKSPELQAEAKSYFEKSKEQLTPLIKKAGTELVNFLSYFVELGTQPATQDYKDDDDKGHHHHHHHHGGQ

生化/生理作用

SILu^?Prot APOA2 is a recombinant, stable isotope-labeled human APOA2 which incorporates [¹³C₆,¹⁵N₄]-Arginine and [¹³C₆,¹⁵N₄]-Lysine. Expressed in human 293 cells, it is designed to be used as an internal standard for bioanalysis of APOA2 in mass-spectrometry. SILu Prot APOA2 is a homodimer of 97 amino acids (including C-terminal polyhistidine and FLAG^?tags), with a calculated molecular mass of 11 kDa.

外形

Supplied as a lyophilized powder containing phosphate buffered saline.

法律信息

This product is licensed under U.S. Patent No. 7,396,688 and foreign counterparts from E. I. du Pont de Nemours and Company. The purchase of this product conveys to the buyer the nontransferable right to use the purchased amount of the product for research and development only, including services for a third party for consideration. The buyer cannot sell or otherwise transfer this product, its components or materials made using this product or its components to a third party. Information about licenses for excluded uses is available from: E. I. du Pont de Nemours and Company; Attn: Associate Director, Commercial Development; DuPont Experimental Station E268; 200 Powdermill Rd.; Wilmington, DE 19803; 1-877-881-9787 (voice), 1-302-695-1437 (fax), licensing@dupont.com.
FLAG is a registered trademark of sigma-aldrich Co. LLC
SILu is a trademark of sigma-aldrich Co. LLC

基本信息

NACRES

NA.12

半岛bd体育手机客户端 性质

质量水平	200
生物来源	human
重组	expressed in HEK 293 cells
标签	8-His tagged
测定	≥98% (SDS-PAGE)
形式	lyophilized powder
效能	≥98% Heavy amino acids incorporation efficiency by MS
technique(s)	mass spectrometry (MS): suitable
适用性	suitable for mass spectrometry (standard)
UniProt登记号	P02652
储存温度	?20℃
Gene Information	human ... APOA2(336)

安全信息

储存分类代码	11 - Combustible Solids
WGK	WGK 2
闪点(F)	Not applicable
闪点(C)	Not applicable