半岛bd体育手机客户端 说明
一般描述
Interferon gamma (IFNγ) is a dimerized soluble cytokine that is the only member of the type II class of interferons. IFNγ is secreted by T helper cells (specifically, Th1 cells), cytotoxic T cells (TC cells) and Natural killer (NK) cells. When combined with other inflammatory cytokines, evaluating the levels of IFNγ can be used as a diagnostic tool in patients with breast cancer or benign prostatic hyperplasia. A recent study evaluated the effect of a cancer vaccine given to patients with colorectal cancer, on the levels of plasma pro-inflammatory cytokines (including IFN-γ). The study concluded that patients achieving stable disease showed increasing levels of plasma inflammatory cytokines.
免疫原
QDPYVKEAENLKKYFNAGHSDVADNGTLFLGILKNWKEESDRKIMQSQIVSFYFKLFKNFKDDQSIQKSVETIKEDMNVKFFNSNKKKRDDFEKLTNYSVTDLNVQRKAIHELIQVMAELSPAAKTGKRKRSQMLFRG
生化/生理作用
SILu?Lite IFNG is a recombinant human protein expressed in human 293 cells. It is a homodimer consisting of 138 amino acids Expressed in human 293 cells, with a calculated molecular mass of 17 kDa. SILu Lite IFNG is an analytical standard designed to be used as starting material for preparation of calibrators and controls in LC-MS applications.
外形
Lyophilized from a solution of phosphate buffered saline.
法律信息
SILu is a trademark of sigma-aldrich Co. LLC
基本信息
NACRES | NA.12 |
半岛bd体育手机客户端 性质
质量水平 | 200 |
生物来源 | human |
重组 | expressed in HEK 293 cells |
测定 | ≥98% (SDS-PAGE) |
形式 | lyophilized powder |
效能 | ≥98% Heavy amino acids incorporation efficiency by MS |
分子量 | calculated mol wt 17 kDa |
technique(s) | mass spectrometry (MS): suitable |
适用性 | suitable for mass spectrometry (internal calibrator) |
UniProt登记号 | P01579 |
储存温度 | ?20℃ |
Gene Information | human ... IFNG(3458) |
安全信息
储存分类代码 | 11 - Combustible Solids |
WGK | WGK 2 |
闪点(F) | Not applicable |
闪点(C) | Not applicable |