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位置: 首页> 品牌> Sigma-Aldrich> SILuTMLite CLU Clusterin human

SILuTMLite CLU Clusterin human

品牌
Sigma-Aldrich
货号
MSST0008
规格纯度
recombinant, expressed in HEK 293 cells, MS Protein Standard
价格
11120.3 *本价格含增值税费
促销
服务
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数量
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半岛bd体育手机客户端 名称:
SILu TMLite CLU Clusterin human
Apolipoprotein J
Clusterin
Testosterone-repressed prostate message 2 (TRPM-2)
半岛bd体育手机客户端 介绍:

半岛bd体育手机客户端 说明

一般描述

SILu?Lite Clusterin is a recombinant human protein expressed in human 293 cells. It is a heterodimer of 2 subunits (alpha and beta) consisting of 427 amino acids (including N-terminal polyhistidine and V5 tags), with a calculated molecular weight of 50 kDa. SILu?Lite Clusterin is designed to be used as an internal standard for bioanalysis of Clusterin in mass-spectrometry.

生化/生理作用

Clusterin is a secreted glycosylated, 80-kDa disulfide-linked heterodimer of alpha and beta subunits (produced by internal cleavage). Clusterin is expressed in virtually all tissues and found in all human fluids. It is involved in numerous physiological processes important for carcinogenesis and tumor growth, including anti-apoptotic cell survival, cell cycle regulation, cell adhesion, tissue remodeling and lipid transportation. Clusterin also exists as a nuclear protein. The secreted form of Clusterin has extracellular chaperone and anti-apoptotic activities while the nuclear form acts as a proapoptotic factor.

序列

DQTVSDNELQEMSNQGSKYVNKEIQNAVNGVKQIKTLIEKTNEERKTLLSNLEEAKKKKEDALNETRESETKLKELPGVCNETMMALWEECKPCLKQTCMKFYARVCRSGSGLVGRQLEEFLNQSSPFYFWMNGDRIDSLLENDRQQTHMLDVMQDHFSRASSIIDELFQDRFFTREPQDTYHYLPFSLPHRRPHFFFPKSRIVRSLMPFSPYEPLNFHAMFQPFLEMIHEAQQAMDIHFHSPAFQHPPTEFIREGDDDRTVCREIRHNSTGCLRMKDQCDKCREILSVDCSTNNPSQAKLRRELDESLQVAERLTRKYNELLKSYQWKMLNTSSLLEQLNEQFNWVSRLANLTQGEDQYYLRVTTVASHTSDSDVPSGVTEVVVKLFDSDPITVTVPVEVSRKNPKFMETVAEKALQEYRKKHREESDPSRGPFEGKPIPNPLLGLDSTRTGHHHHHHHHGGQ

外形

Supplied as a lyophilized powder containing phosphate buffered saline.

法律信息

This product is licensed under U.S. Patent No. 7,396,688 and foreign counterparts from E. I. du Pont de Nemours and Company. The purchase of this product conveys to the buyer the nontransferable right to use the purchased amount of the product for research and development only, including services for a third party for consideration. The buyer cannot sell or otherwise transfer this product, its components or materials made using this product or its components to a third party. Information about licenses for excluded uses is available from: E. I. du Pont de Nemours and Company; Attn: Associate Director, Commercial Development; DuPont Experimental Station E268; 200 Powdermill Rd.; Wilmington, DE 19803; 1-877-881-9787 (voice), 1-302-695-1437 (fax), licensing@dupont.com.
SILu is a trademark of sigma-aldrich Co. LLC

半岛bd体育手机客户端 性质

质量水平 200
生物来源 human
重组 expressed in HEK 293 cells
测定 ≥98% (SDS-PAGE)
形式 lyophilized powder
technique(s) mass spectrometry (MS): suitable
适用性 suitable for mass spectrometry (internal calibrator)
UniProt登记号 P10909
储存温度 ?20℃
Gene Information human ... CLU(1191)

安全信息

储存分类代码 13 - Non Combustible Solids
WGK WGK 1
闪点(F) Not applicable
闪点(C) Not applicable

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