半岛bd体育手机客户端 说明
一般描述
A cell-permeable inhibitor of nitric oxide synthase that exhibits about 17-fold greater selectivity for rat neuronal nitric oxide synthase (IC50= 300 nM) compared to the endothelial enzyme (IC50= 5.4 ?M).
A cell-permeable, inhibitor of nitric oxide synthase that exhibits about 17-fold greater selectivity for rat neuronal nitric oxide synthase (IC50= 300 nM) compared to the endothelial enzyme (IC50= 5.4 ?M).
包装
10 mg in Plastic ampoule
Packaged under inert gas
生化/生理作用
Cell permeable: yes
Primary Target
Rat neuronal nitric oxide synthase
Product does not compete with ATP.
Reversible: no
Target IC50: 300 nM for rat neuronal nitric oxide synthase
警告
Toxicity: Standard Handling (A)
其他说明
Krishnaswamy, N., et al. 1995.J. Biol. Chem.270,11103.
Furfine, E.S., et al. 1994.J. Biol. Chem.269,26677.
Narayanan, K., and Griffith, O.W. 1994.J. Med. Chem.37,885.
法律信息
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
基本信息
经验(实验)分子式 | C7H15N3O2S · 2HCl |
分子量 | 278.20 |
半岛bd体育手机客户端 性质
质量水平 | 100 |
测定 | ≥95% (HPLC) |
形式 | solid |
manufacturer/tradename | Calbiochem? |
储存条件 | OK to freeze desiccated (hygroscopic) |
颜色 | white to off-white |
溶解性 | water: 50 mg/mL |
运输 | ambient |
储存温度 | 2-8℃ |
InChI | 1S/C7H15N3O2S/c1-13-7(9)10-4-2-3-5(8)6(11)12/h5H,2-4,8H2,1H3,(H2,9,10)(H,11,12)/t5-/m0/s1 |
InChI key | NGVMVBQRKZPFLB-YFKPBYRVSA-N |
安全信息
储存分类代码 | 11 - Combustible Solids |
WGK | WGK 3 |
Sigma-Aldrich