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位置: 首页> 品牌> Sigma-Aldrich> RNA Polymerase III Inhibitor-CAS 577784-91-9-Calbiochem

RNA Polymerase III Inhibitor-CAS 577784-91-9-Calbiochem

品牌
Sigma-Aldrich
CAS
577784-91-9
货号
557403
规格纯度
RNA Polymerase III Inhibitor, CAS 577784-91-9, is a cell-permeable inhibitor of RNA Polymerase III (IC50= 27 and 32 μM for human and S. cerevisiae RNA Pol III, respectively).
价格
5167.48 *本价格含增值税费
促销
服务
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数量
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半岛bd体育手机客户端 名称:
577784-91-9
RNA Polymerase III Inhibitor-CAS 577784-91-9-Calbiochem
ML-60218, N-[1-(3-(5-Chloro-3-methylbenzo[b]thiophen-2-yl-1-methyl-1H-pyrazol-5-yl)]-2-chlorobenzenesulfonamide
半岛bd体育手机客户端 介绍:

半岛bd体育手机客户端 说明

一般描述

A cell-permeable indazolo-sulfonamide compound that displays broad-spectrum inhibitory activity against RNA Polymerase III (IC50= 27 and 32 ?M for human andS. cerevisiaeRNA Pol III, respectively). Inhibits cell growth in yeast by preventing RNA Pol III-mediated tRNA transcription. Also available as a 25 mM solution in DMSO (Cat. No. 557404).
A cell-permeable inhibitor of RNA polymerase III (RNA Pol III) (IC50= 27 ?M for human RNA Pol III and 32 ?M forSaccharomyces cerevisiaeRNA Pol III). Inhibits cell growth in yeast by preventing RNA Pol III-mediated tRNA transcription.

包装

10 mg in Plastic ampoule
Packaged under inert gas

生化/生理作用

Product does not compete with ATP.
Cell permeable: yes
Primary Target
activity against RNA Polymerase III
Reversible: no
Target IC50: 27 and 32 ?M for Human and S. cerevisiae RNA Pol III

警告

Toxicity: Carcinogenic / Teratogenic (D)

制备说明

Slight warming may be necessary to achieve complete solubilization.

重悬

Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.

其他说明

Wu, L., et al. 2003.Euk. Cell2,256.

法律信息

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

基本信息

经验(实验)分子式 C19H15Cl2N3O2S2
分子量 452.38

半岛bd体育手机客户端 性质

质量水平 100
测定 ≥95% (HPLC)
形式 solid
manufacturer/tradename Calbiochem?
储存条件 OK to freeze
protect from light
颜色 off-white
溶解性 DMSO: 15 mg/mL
运输 ambient
储存温度 2-8℃

安全信息

储存分类代码 11 - Combustible Solids
WGK WGK 1
闪点(F) Not applicable
闪点(C) Not applicable

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