半岛bd体育手机客户端 说明
一般描述
Selective inhibitor of DAG lipase activity in canine platelets (IC50= 4 nM) and in a variety of mammalian cells. Also inhibits glucose- and carbachol-induced insulin release from intact islets. An inhibitor of Angiotensin II (Cat. No. 05-23-0101) and ATP-induced synthesis of 6-keto-prostaglandin F1α.
Selective inhibitor of DAG lipase activity in canine platelets (IC50= 4 nM) and in a variety of mammalian cells. Also inhibits glucose- and carbachol-induced insulin release from intact islets. An inhibitor of Angiotensin II and ATP-induced synthesis of 6-keto-prostaglandin F1α.
包装
10 mg in Plastic ampoule
生化/生理作用
Product does not compete with ATP.
Reversible: no
Cell permeable: no
Primary Target
DAG lipase
Target IC50: 4 nM against DAG lipase activity in canine platelets
警告
Toxicity: Standard Handling (A)
重悬
Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
其他说明
Shinoda, J., et al. 1997.Arterioscler. Thromb. Vasc. Biol.17,295.
Shinoda, J., et al. 1997.Eur. J. Endocrinol.136,207.
Konrad, R.J., et al. 1994.Biochemistry33,13284.
Mason-Garcia, M., et al. 1992.Am. J. Physiol.262,C1197.
Balsinde, J., et al. 1991.J. Biol. Chem.266,15638.
法律信息
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
基本信息
| 经验(实验)分子式 | C20H34N4O4 |
| 分子量 | 394.51 |
| MDL编号 | MFCD00210844 |
半岛bd体育手机客户端 性质
| 质量水平 | 100 |
| 测定 | ≥98% (HPLC) |
| 形式 | solid |
| manufacturer/tradename | Calbiochem? |
| 储存条件 | OK to freeze |
| 颜色 | white to off-white |
| 溶解性 | DMSO: 25 mg/mL ethanol: 25 mg/mL |
| 运输 | ambient |
| 储存温度 | 10-30℃ |
| InChI | 1S/C20H34N4O4/c25-19(27-23-17-11-5-3-6-12-17)21-15-9-1-2-10-16-22-20(26)28-24-18-13-7-4-8-14-18/h1-16H2,(H,21,25)(H,22,26) |
| InChI key | RXSVYGIGWRDVQC-UHFFFAOYSA-N |
安全信息
| 储存分类代码 | 11 - Combustible Solids |
| WGK | WGK 3 |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
Sigma-Aldrich
m.cnreagent.com
