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位置: 首页> 品牌> Sigma-Aldrich> Propargyl-PEG3-acid

Propargyl-PEG3-acid

品牌
Sigma-Aldrich
CAS
1347760-82-0
货号
901565
包装型号
规格纯度
价格
1098.63 *本价格含增值税费
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半岛bd体育手机客户端 名称:
1347760-82-0
Propargyl-PEG 3-acid
半岛bd体育手机客户端 介绍:

半岛bd体育手机客户端 说明

应用

Propargyl-PEG3-acid is a heterobifunctional, PEGylated crosslinker featuring a carboxylic acid at one end and propargyl group at the other for reaction with azide-containing compounds using click chemistry. The hydrophillic PEG linker facilitates solubility in biological applications. Propargyl-PEG3-acid can be used for bioconjugation or as a building block for synthesis of small molecules, conjugates of small molecules and/or biomolecules, or other tool compounds for chemical biology and medicinal chemistry that require ligation. Examples of applications include its synthetic incorporation into antibody-drug conjugates or proteolysis-targeting chimeras (PROTAC?molecules) for targeted protein degradation.
This is a crosslinker with an alkyne group on one end and a carboxyl group on the other end. The alkyne can be used to attach to an azide using copper-catalyzed click chemistry. The compound contains three PEG units to help improve solubility.

法律信息

PROTAC is a registered trademark of Arvinas Operations, Inc., and is used under license

基本信息

经验(实验)分子式 C10H16O5
分子量 216.23
MDL编号 MFCD22201521
NACRES NA.22

半岛bd体育手机客户端 性质

形式 liquid
储存温度 ?20℃
SMILES string C#CCOCCOCCOCCC(O)=O

安全信息

储存分类代码 12 - Non Combustible Liquids
WGK WGK 3

Sigma-Aldrich

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