您好,欢迎来到半岛电竞官方网址 ! [ 登录] [ 免费注册]
半岛电竞官方网址
位置: 首页> 品牌> Sigma-Aldrich> Propargyl-PEG2-acid

Propargyl-PEG2-acid

品牌
Sigma-Aldrich
CAS
1859379-85-3
货号
901566
包装型号
规格纯度
价格
1526.69 *本价格含增值税费
促销
服务
  • 原厂保证
  • 包邮
  • 增值税票
数量
- +
半岛bd体育手机客户端 名称:
1859379-85-3
Propargyl-PEG 2-acid
半岛bd体育手机客户端 介绍:

半岛bd体育手机客户端 说明

应用

Propargyl-PEG2-acid is a heterobifunctional, PEGylated crosslinker featuring a carboxylic acid at one end and propargyl group at the other for reaction with azide-containing compounds using click chemistry. The hydrophillic PEG linker facilitates solubility in biological applications. Propargyl-PEG2-acid can be used for bioconjugation or as a building block for synthesis of small molecules, conjugates of small molecules and/or biomolecules, or other tool compounds for chemical biology and medicinal chemistry that require ligation. Examples of applications include its synthetic incorporation into antibody-drug conjugates or proteolysis-targeting chimeras (PROTAC?molecules) for targeted protein degradation.
This is a crosslinker with an alkyne group on one end and a carboxyl group on the other end. The alkyne can be used to attach to an azide using copper-catalyzed click chemistry. The compound contains two PEG units to help improve solubility.

法律信息

PROTAC is a registered trademark of Arvinas Operations, Inc., and is used under license

基本信息

经验(实验)分子式 C8H12O4
分子量 172.18
NACRES NA.22

半岛bd体育手机客户端 性质

形式 liquid
reaction suitability reaction type: click chemistry
储存温度 ?20℃
SMILES string C#CCOCCOCCC(O)=O

安全信息

储存分类代码 13 - Non Combustible Solids
WGK WGK 3

Sigma-Aldrich

推荐半岛bd体育手机客户端
Baidu
map