半岛bd体育手机客户端 说明
一般描述
Highly purified preparation of an altered form of human PAI-1 containing four mutated amino acids. Mutant PAI-1 is virtually unable to go latent and is stable at elevated temperature and pH for extended periods of time (t?= 145 hours at 37°C, pH 7.4). Inhibits uPA (Ki= 5.1 x 106M-1sec-1) and tPA (Ki= 7.9 x 105M-1sec-1).
Highly purified preparation of an altered form of human PAI-1 containing four mutated amino acids. Mutant PAI-1 is virtually unable to go latent and is stable at elevated temperature and pH for extended periods of time (t?= 145 h at 37°C, pH 7.4). Inhibits uPA (Ki= 5.1 x 106M-1sec-1) and tPA (Ki= 7.9 x 105M-1sec-1).
包装
50 μg in Plastic ampoule
Please refer to vial label for lot-specific concentration.
生化/生理作用
≥90% by uPA assay.
Product does not compete with ATP.
Primary Target
Plasminogen Activator
Target Ki: 5.1 x 106 M-1 sec-1, 7.9 x 105 M-1 sec-1 against uPA and tPA, respectively
Reversible: no
Cell permeable: no
警告
Toxicity: Standard Handling (A)
外形
In 100 mM NaCl, 50 mM sodium phosphate buffer, 1 mM EDTA, pH 6.6.
重悬
Following initial thaw, aliquot and freeze (-70°C).
其他说明
Berkenpas, M.B., et al. 1995.EMBO J.14,2969.
法律信息
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
半岛bd体育手机客户端 性质
| 质量水平 | 100 |
| 测定 | ≥95% (SDS-PAGE) |
| 形式 | liquid |
| manufacturer/tradename | Calbiochem? |
| 储存条件 | OK to freeze avoid repeated freeze/thaw cycles |
| 运输 | wet ice |
| 储存温度 | ?70℃ |
安全信息
| 储存分类代码 | 10 - Combustible liquids |
| WGK | WGK 1 |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
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