MultiScreen IP Filter Plate, 0.45 μm, clear, non-sterile

半岛bd体育手机客户端 说明

一般描述

Filter Code: IP
Increasing drug candidate predictability earlier in the discovery pipeline using non-cell-based assays can improve candidate throughput during the ADME stage. Non-cell-based permeability assays are predictive models for oral absorption of development candidates.

MultiScreen Permeability, MultiScreen-IP, and MultiScreen Acceptor plates support artificial membrane strategies for predicting passive transport.

Membranes have uniform pore structure and density for reliable transport:
- Individual wells minimize candidate cross-talk
- Compatibility with automated liquid handling systems increases throughput

Permeability Assay:
- The MultiScreen Permeability plate has a polycarbonate membrane, which supports a hexane/hexadecane artificial layer for permeability assays.1

PAMPA Assay:
- The MultiScreen-IP plate has a hydrophobic PVDF membrane, which supports a lipid bilayer for PAMPA asays.2,3

MultiScreen Acceptor Plate:
- The MultiScreen Acceptor plate can be used with either plate to capture passively transported compounds. Constructed of 100% PTFE, the plate can improve LC/MS results depending on the charge of the small molecules being evaluated.

应用

Research Category
Assays

Protein

外形

Color Code: 透明

其他说明

Automation Compatible: No

法律信息

Immobilon is a registered trademark of Merck KGaA, Darmstadt, Germany
MULTISCREEN is a registered trademark of Merck KGaA, Darmstadt, Germany

基本信息

eCl@ss	32039006
NACRES	NB.22

半岛bd体育手机客户端 性质

物料	PVDF membrane (hydrophobic) acrylic flat bottom wells
质量水平	400
无菌性	non-sterile
半岛bd体育手机客户端 线	MultiScreen?
特点	hydrophobic lid
manufacturer/tradename	MultiScreen?
technique(s)	parallel artificial membrane permeation assay (PAMPA): suitable
板尺寸	96 wells
孔最大体积	300 μL
工作体积	50-250 μL
基质	Immobilon?-P
孔径	0.45 μm pore size
试验参数	sample volume: 50-250 μL (per well)
binding type	high binding surface
运输	ambient