半岛bd体育手机客户端 说明
一般描述
A cell-permeable, selective inhibitor of cGMP-inhibited phosphodiesterase (PDE III, IC50= 300 nM). Has positive chronotropic, ionotropic, and vasodilatory effects on the heart.
A cell-permeable, selective inhibitor of cGMP-inhibited phosphodiesterase (PDE III; IC50= 300 nM). Has positive chronotropic, inotropic, and vasodilatory effects on the heart.
包装
10 mg in Alu drum
生化/生理作用
Cell permeable: yes
Primary Target
PDE 3
Product does not compete with ATP.
Reversible: no
Target IC50: 300 nM against PDE III
警告
Toxicity: Toxic (F)
重悬
Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 2 months at -20°C.
其他说明
Bailey, J.M., et al. 1994.Anesthesiology81,616.
Wilhelm, D., et al. 1992.J. Cardiovasc. Pharmacol.20,705.
Lindgren, S.H., et al. 1990.Acta. Phys. Scand.140,209.
Harrison, S.A., et al. 1986.Mol. Pharmacol.29,506.
Due to the nature of the Hazardous Materials in this shipment, additional shipping charges may be applied to your order. Certain sizes may be exempt from the additional hazardous materials shipping charges. Please contact your local sales office for more information regarding these charges.
法律信息
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
基本信息
| 经验(实验)分子式 | C12H9N3O |
| 分子量 | 211.22 |
| MDL编号 | MFCD00133539 |
半岛bd体育手机客户端 性质
| 质量水平 | 100 |
| 测定 | ≥99% (HPLC) |
| 形式 | solid |
| manufacturer/tradename | Calbiochem? |
| 储存条件 | OK to freeze |
| 颜色 | white |
| 溶解性 | DMSO: 20 mg/mL ethanol: 3 mg/mL |
| 运输 | ambient |
| 储存温度 | ?20℃ |
| InChI | 1S/C12H9N3O/c1-8-11(9-2-4-14-5-3-9)6-10(7-13)12(16)15-8/h2-6H,1H3,(H,15,16) |
| InChI key | PZRHRDRVRGEVNW-UHFFFAOYSA-N |
安全信息
| 象形图 |  |
| 警示用语： | Danger |
| 危险声明 | H301 |
| 预防措施声明 | P264 - P270 - P301 + P310 - P405 - P501 |
| 危险分类 | Acute Tox. 3 Oral |
| 储存分类代码 | 6.1C - Combustible, acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects |
| WGK | WGK 3 |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
Sigma-Aldrich
m.cnreagent.com
