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位置: 首页> 品牌> Sigma-Aldrich> Ketoconazole-CAS 65277-42-1-Calbiochem

Ketoconazole-CAS 65277-42-1-Calbiochem

品牌
Sigma-Aldrich
CAS
65277-42-1
货号
420600
规格纯度
An inhibitor of cytochrome P-450 in steroid biosynthesis. An antifungal agent that displays potent anti-metastatic, anti-neoplastic, and anti-psoriatic activities.
价格
1868.1 *本价格含增值税费
促销
服务
  • 原厂保证
  • 包邮
  • 增值税票
数量
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半岛bd体育手机客户端 名称:
65277-42-1
Ketoconazole-CAS 65277-42-1-Calbiochem
cis-1-Acetyl-4-[4-[[2-(2,4-dichlorophenyl)-2-(1H-imidazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy]phenyl]piperazine, R-41400, CYP17A1 Inhibitor I
半岛bd体育手机客户端 介绍:

半岛bd体育手机客户端 说明

一般描述

An inhibitor of cytochrome P-450 in steroid biosynthesis. An anti-fungal agent that displays potent anti-metastatic, anti-neoplastic, and anti-psoriatic activities. Also acts as an inhibitor of 5-lipoxygenase (5-LO; IC50= 26 ?M) and thromboxane synthase activities.
An inhibitor of cytochrome P-450 in steroid biosynthesis. An antifungal agent that displays potent anti-metastatic, anti-neoplastic, and anti-psoriatic activities. Also acts as an inhibitor of 5-lipoxygenase (5-LO; IC50= 26 ?M) and thromboxane synthase activities.

包装

50 mg in Glass bottle

生化/生理作用

Primary Target
5-LO

警告

Toxicity: Toxic & Carcinogenic / Teratogenic (G)

其他说明

van Wauwe, J.P., and Janssen, P.A.J. 1989.J. Med. Chem.32,2231.
Beetens, J.R., et al. 1986.Biochem. Pharmacol.35,883.
Lambert, A., et al. 1986.Biochem. Pharmacol.35,3999.
Tucker, W.F.G., and MacNeil, S. 1986.Br. Med. J.293,882.
Lelcuk, S., et al. 1984.J. Trauma24,393.
Due to the nature of the Hazardous Materials in this shipment, additional shipping charges may be applied to your order. Certain sizes may be exempt from the additional hazardous materials shipping charges. Please contact your local sales office for more information regarding these charges.

法律信息

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

基本信息

经验(实验)分子式 C26H28Cl2N4O4
分子量 531.43
MDL编号 MFCD00058579

半岛bd体育手机客户端 性质

质量水平 100
测定 ≥98% (HPLC)
形式 solid
效能 26 μM IC50
manufacturer/tradename Calbiochem?
储存条件 OK to freeze
颜色 off-white
运输 ambient
储存温度 2-8℃
InChI 1S/C26H28Cl2N4O4/c1-19(33)31-10-12-32(13-11-31)21-3-5-22(6-4-21)34-15-23-16-35-26(36-23,17-30-9-8-29-18-30)24-7-2-20(27)14-25(24)28/h2-9,14,18,23H,10-13,15-17H2,1H3/t23-,26-/m1/s1
InChI key XMAYWYJOQHXEEK-ZEQKJWHPSA-N

安全信息

象形图 GHS06GHS08GHS09
警示用语: Danger
危险声明 H301 - H360F - H373 - H410
预防措施声明 P201 - P202 - P260 - P264 - P273 - P301 + P310
危险分类 Acute Tox. 3 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - Repr. 1B - STOT RE 2
储存分类代码 6.1C - Combustible, acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
WGK WGK 3
闪点(F) Not applicable
闪点(C) Not applicable

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