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InSolution 5-Aza-2'-Deoxycytidine-CAS 2353-33-5-Calbiochem

品牌
Sigma-Aldrich
CAS
2353-33-5
货号
189826
规格纯度
A cytosine analog that acts as a DNA methyltransferase inhibitor. Restores caspase-8 and caspase-10 mRNA and protein expression as well as TRAIL (Tumor necrosis factor-Related Apoptosis Inducing Ligand) sensitivity in TRAIL-resistant cell lines.
价格
2096.01 *本价格含增值税费
促销
服务
  • 原厂保证
  • 包邮
  • 增值税票
数量
- +
半岛bd体育手机客户端 名称:
2353-33-5
InSolution 5-Aza-2'-Deoxycytidine-CAS 2353-33-5-Calbiochem
Decitabine
半岛bd体育手机客户端 介绍:

半岛bd体育手机客户端 说明

一般描述

A cytosine analog that acts as a DNA methyltransferase inhibitor. Restores caspase-8 and caspase-10 mRNA and protein expression as well as TRAIL (Tumor necrosis factor-Related Apoptosis Inducing Ligand) sensitivity in TRAIL-resistant cell lines. Also enhances apoptosis induced by HDAC (Histone Deacetylase) inhibitors. The solid form of this compound (Cat. No. 189825) is also available.

包装

10 mg in Glass bottle
Packaged under inert gas

警告

Toxicity: Regulatory Review (Z)

外形

A 100 mM (10 mg/438 ?l) solution of 5-Aza-2?-Deoxycytidine (Cat. No. 189825) in DMSO.

其他说明

Eggert, A., et al. 2001.Cancer Res.61,1314.
Takebayashi, S., et al. 2001.Biochem. Biophys. Res. Commun.288,921.
Zhu, W.G., et al. 2001.Cancer Res.61,1327.
Hopkins-Donaldson, S., et al. 2000.Cancer Res.60,4315.
Haaf, T. 1995.Pharmacol. Ther.65,19.
Jones, P.A., and Taylor, S.M. 1980.Cell20,85.

法律信息

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

基本信息

经验(实验)分子式 C8H12N4O4
分子量 228.21
MDL编号 MFCD00043011

半岛bd体育手机客户端 性质

质量水平 100
测定 ≥98% (HPLC)
形式 liquid
manufacturer/tradename Calbiochem?
储存条件 OK to freeze
desiccated (hygroscopic)
protect from light
运输 ambient
储存温度 ?20℃
InChI 1S/C8H12N4O4/c9-7-10-3-12(8(15)11-7)6-1-4(14)5(2-13)16-6/h3-6,13-14H,1-2H2,(H2,9,11,15)
InChI key XAUDJQYHKZQPEU-UHFFFAOYSA-N

Sigma-Aldrich

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