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Honokiol-CAS 35354-74-6-Calbiochem

品牌
Sigma-Aldrich
CAS
35354-74-6
货号
384620
规格纯度
A biphenyl neolignan and an active principle of Magnolia extract that displays anti-angiogenic, anti-tumor and anxiolytic properties.
价格
1977.69 *本价格含增值税费
促销
服务
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  • 包邮
  • 增值税票
数量
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半岛bd体育手机客户端 名称:
35354-74-6
Honokiol-CAS 35354-74-6-Calbiochem
5,3'-Diallyl-2,4'-dihydroxydiphenyl, VEGFR Tyrosine Kinase Inhibitor XIX, VEGFR2 Kinase Inhibitor XV
半岛bd体育手机客户端 介绍:

半岛bd体育手机客户端 说明

一般描述

A biphenyl neolignan and an active principle of Magnolia extract that displays anti-angiogenic, anti-tumor and anxiolytic properties. Shown to induce apoptosis and preferentially inhibit the growth of primary human endothelial cells over fibroblasts by blocking VEGFR2 autophosphorylation and subsequent rac activation. Also blocks thein vivogrowth of SVR angiosarcoma in nude mice.
The active principle of Magnolia extracts that exhibits anti-angiogenic, anti-tumor, anxiolytic, and chemoprotective properties. Shown to induce apoptosis and preferentially inhibit the growth of primary human endothelial cells over fibroblasts by blocking vascular endothelial growth factor receptor 2 (VEGFR2) autophosphorylation and subsequent rac activation. Also shown to block the growth of SVR angiosarcoma in nude mice.

包装

10 mg in Plastic ampoule
Packaged under inert gas

生化/生理作用

Product does not compete with ATP.
Reversible: no
Cell permeable: no
Primary Target
Anti-angiogenic, anti-tumor and anxiolytic properties

警告

Toxicity: Standard Handling (A)

重悬

Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.

其他说明

Bai, X., et al. 2003.J. Biol. Chem.278,35501.
Yang, S.E., et al. 2002.Biochem. Pharmacol.63,1641.
Son, H.J., et al. 2000.Planta Med.66,469.
Maruyama, Y., et al. 1998.J. Nat. Prod.61,135.

法律信息

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

基本信息

经验(实验)分子式 C18H18O2
分子量 266.33
MDL编号 MFCD00016674

半岛bd体育手机客户端 性质

质量水平 100
测定 ≥98% (HPLC)
形式 solid
manufacturer/tradename Calbiochem?
储存条件 OK to freeze
protect from light
颜色 white
溶解性 DMSO: 10 mg/mL
ethanol: soluble
运输 ambient
储存温度 2-8℃
InChI 1S/C18H18O2/c1-3-5-13-7-9-18(20)16(11-13)14-8-10-17(19)15(12-14)6-4-2/h3-4,7-12,19-20H,1-2,5-6H2
InChI key FVYXIJYOAGAUQK-UHFFFAOYSA-N

安全信息

象形图 GHS05GHS09
警示用语: Danger
危险声明 H318 - H411
预防措施声明 P273 - P280 - P305 + P351 + P338 - P391 - P501
危险分类 Aquatic Chronic 2 - Eye Dam. 1
储存分类代码 11 - Combustible Solids
WGK WGK 3
闪点(F) Not applicable
闪点(C) Not applicable

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