半岛bd体育手机客户端 说明

一般描述

Cell-permeable derivative of glutathione (GSH) that undergoes hydrolysis by intracellular esterases thereby increasing intracellular GSH concentration in many tissues and cell types. Effective transport of GSH-MEE has been used to protect cells against radiation damage, oxidants and various toxic compounds including heavy metals. A protective agent against cellular damage, such as cataracts and mitochondrial degeneration.
Cell-permeable derivative of glutathione (GSH) that undergoes hydrolysis by intracellular esterases to release GSH. Effective transport of GSH-MEE has been used to protect cells against damage from radiation, oxidants, and various toxic compounds including heavy metals. A protective agent against cellular damage such as in cataracts and mitochondrial degeneration.

包装

50 mg in Glass bottle
Packaged under inert gas

生化/生理作用

Primary Target
Effective transport of GSH-MEE
Product does not compete with ATP.
Reversible: no
Cell permeable: no

警告

Toxicity: Standard Handling (A)

重悬

Following reconstitution, aliquot and freeze (-20°C). Unstable in solution; reconstitute just prior to use.

其他说明

Grattagliano, I., et al. 1995.J. Pharmacol. Exp. Ther.272,484.
Martensson, J., et al. 1993.Proc. Natl. Acad. Sci. USA90,317.
Anderson, M.E., and Meister, A. 1989.Anal. Biochem.183,16.
Anderson, M.E., et al. 1985.Arch. Biochem. Biophys.239,538.
Wellner, V.P., et al. 1984.Proc. Natl. Acad. Sci. USA81,4732.
Puri, R.N., and Meister, A. 1983.Proc. Natl. Acad. Sci. USA80,5258.

法律信息

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

基本信息

经验(实验)分子式	C12H21N3O6S
分子量	335.38

半岛bd体育手机客户端 性质

质量水平	100
测定	>90% (TLC)
形式	solid
manufacturer/tradename	Calbiochem?
储存条件	OK to freeze desiccated (hygroscopic)
颜色	white
溶解性	water: 50 mg/mL
运输	ambient
储存温度	?20℃
InChI	1S/C12H21N3O6S/c1-2-21-10(17)5-14-11(18)8(6-22)15-9(16)4-3-7(13)12(19)20/h7-8,22H,2-6,13H2,1H3,(H,14,18)(H,15,16)(H,19,20)/t7-,8-/m0/s1
InChI key	JKRODHBGNBKZLE-YUMQZZPRSA-N

安全信息

储存分类代码	11 - Combustible Solids
WGK	WGK 1
闪点(F)	Not applicable
闪点(C)	Not applicable