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Glucose Transporter Inhibitor III, STF-31-Calbiochem

品牌
Sigma-Aldrich
货号
351801
规格纯度
The Glucose Transporter Inhibitor III, STF-31 controls the biological activity of Glucose Transporter.
价格
2165.23 *本价格含增值税费
促销
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数量
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半岛bd体育手机客户端 名称:
Glucose Transporter Inhibitor III, STF-31-Calbiochem
STF-31
半岛bd体育手机客户端 介绍:

半岛bd体育手机客户端 说明

一般描述

A cell-permeable sulfonamide that selectively inhibits the growth of VHL-deficient renal cell carcinomas (RCCs) dose-dependently (0-5 ?M) by directly targeting glucose transporter 1 (GLUT1), which is up-regulated by HIF (hypoxia-inducible factor) transcription factor in VHL-deficient cells. It elicits decreased oxidative phosphorylation associated with aerobic glycolysis and leads to necrosis, which is consistent with the effect induced by GLUT1 RNA interference. It does not bind to other glucose transporters, and does not inhibit a broad range of 50 tested kinases.

包装

10 mg in Glass bottle
Packaged under inert gas

警告

Toxicity: Standard Handling (A)

重悬

Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.

其他说明

Chan, D., et al. 2011.Sci. Transl. Med.3,94ra70.

法律信息

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

基本信息

经验(实验)分子式 C23H25N3O3S
分子量 423.53
MDL编号 MFCD04153828

半岛bd体育手机客户端 性质

质量水平 100
测定 ≥99% (HPLC)
形式 solid
manufacturer/tradename Calbiochem?
储存条件 OK to freeze
protect from light
颜色 white
溶解性 DMSO: 50 mg/mL
运输 wet ice
储存温度 2-8℃

安全信息

象形图 GHS07
警示用语: Warning
危险声明 H302
预防措施声明 P264 - P270 - P301 + P312 - P501
危险分类 Acute Tox. 4 Oral
储存分类代码 11 - Combustible Solids
WGK WGK 3
闪点(F) Not applicable
闪点(C) Not applicable

Sigma-Aldrich

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