Galanthamine, Hydrobromide-CAS 69353-21-5-Calbiochem

半岛bd体育手机客户端 说明

一般描述

A competitive and reversible inhibitor of acetylcholinesterase. Antimyasthenic agent. Can partially reverse the effects of scopolamine-induced amnesia in rats. Reported to improve learning and short-term memory in animal models.
Cholinesterase antagonist. Antimyasthenic agent. Can partially reverse the effects of scopolamine-induced amnesia in rats.

生化/生理作用

Primary Target
Acetylcholinesterase
Product competes with ATP.
Cell permeable: no
Reversible: yes

警告

Toxicity: Toxic (F)

重悬

Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.

其他说明

Pilger, C., et al. 2001.J. Mol. Graph. Model19,288.
Iliev, A., et al. 1999.Methods Find. Exp. Clin. Pharmacol.21,297.
Southan, G.J., et al. 1996.Br. J. Pharmacol.117,619.
Mutafova-Yambolieva, V.N., et al. 1993.Gen. Pharmacol.24,1253.
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法律信息

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

基本信息

经验(实验)分子式	C17H21NO3· xHBr
分子量	287.35 (free base basis)

半岛bd体育手机客户端 性质

质量水平	100
测定	≥95% (HPLC)
形式	solid
manufacturer/tradename	Calbiochem?
储存条件	OK to freeze desiccated
颜色	white
溶解性	ethanol: 1 mg/mL water: 1 mg/mL DMSO: 5 mg/mL
运输	ambient
储存温度	2-8℃
InChI	1S/C17H21NO3.BrH/c1-18-8-7-17-6-5-12(19)9-14(17)21-16-13(20-2)4-3-11(10-18)15(16)17;/h3-6,12,14,19H,7-10H2,1-2H3;1H/t12-,14-,17-;/m0./s1
InChI key	QORVDGQLPPAFRS-XPSHAMGMSA-N

安全信息

象形图
警示用语：	Danger
危险声明	H301
预防措施声明	P264 - P270 - P301 + P310 - P405 - P501
危险分类	Acute Tox. 3 Oral
储存分类代码	6.1C - Combustible, acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
WGK	WGK 3
闪点(F)	Not applicable
闪点(C)	Not applicable