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位置: 首页> 品牌> Sigma-Aldrich> N-α-(9-Fluorenylmethyloxycarbonyl)-4-(trifluoromethyldiazirin)- L -phenylalanine

Fmoc- L -Photo-Phe-OH

品牌
Sigma-Aldrich
CAS
133342-64-0
货号
907294
包装型号
规格纯度
≥95%
价格
4179.53 *本价格含增值税费
促销
服务
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数量
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半岛bd体育手机客户端 名称:
133342-64-0
Fmoc- L -Photo-Phe-OH
( S)-2-((((9 H-Fluoren-9-yl)methoxy)carbonyl)amino)-3-(4-(3-(trifluoromethyl)-3 H-diazirin-3-yl)phenyl)propanoic acid
Fmoc-Tdf-OH
Photo-crosslinking amino acid
Photoprobe building block
N-α-(9-Fluorenylmethyloxycarbonyl)-4-(trifluoromethyldiazirin)- L -phenylalanine
Diazirine amino acid
Photo-Phe
半岛bd体育手机客户端 介绍:

半岛bd体育手机客户端 说明

应用

Fmoc- L -Photo-Phe-OH is a diazirine-containing, Fmoc-protected phenylalanine amino acid and multifunctional photo-crosslinker. Its incorporation into peptides or small-molecule probes and tools allows for photoaffinity labeling of cellular targets and protein-protein interactions upon UV light (~360 nm) irradiation to form a covalent bond. This and other multifunctional probe building blocks will continue to accelerate drug discovery research for probing cellular mechanisms, target ID/validation, and understanding traditionally undruggable targets. An unprotected version is also available as 907340.

其他说明

Covalent modifier-type aggregation inhibitor of amyloid-β based on a cyclo-KLVFF motif

Mode of Action of cGMP-dependent Protein Kinase-specific Inhibitors Probed by Photoaffinity Cross-linking Mass Spectrometry

Trifluoromethyldiazirine: an effective photo-induced cross-linking probe for exploring amyloid formation

Simple and Versatile Method for Tagging Phenyldiazirine Photophores

Fishing for Drug Targets: A Focus on Diazirine Photoaffinity Probe Synthesis

Photo-affinity labeling (PAL) in chemical proteomics: a handy tool to investigate protein-protein interactions (PPIs)

基本信息

经验(实验)分子式 C26H20F3N3O4
分子量 495.45
MDL编号 MFCD30187628

半岛bd体育手机客户端 性质

测定 ≥95%
形式 powder
reaction suitability reaction type: Fmoc solid-phase peptide synthesis
application(s) peptide synthesis
官能团 Fmoc
储存温度 ?20℃

安全信息

储存分类代码 11 - Combustible Solids
WGK WGK 3

Sigma-Aldrich

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