FeTMPyP-Calbiochem

品牌

Sigma-Aldrich

货号

341501

包装型号

10 MG, Catalyzes the isomerization of peroxynitrite (ONOO?) to nitrate (NO3?) under physiological conditions and at realistic dose-derived concentrations (k_cat= 2.2 x 10?M

规格纯度

Catalyzes the isomerization of peroxynitrite (ONOO^-) to nitrate (NO3^-) under physiological conditions and at realistic dose-derived concentrations (k_cat= 2.2 x 10⁶M^-¹s^-

价格

1288.09 元 *本价格含增值税费

促销

数量

- +

半岛bd体育手机客户端名称：

FeTMPyP-Calbiochem
5,10,15,20-Tetrakis(N-methyl-4'-pyridyl)porphinato Iron (III) Chloride, Fe ^IIITMPyP(Cl)

半岛bd体育手机客户端介绍：

半岛bd体育手机客户端说明

一般描述

Catalyzes the isomerization of peroxynitrite (ONOO^-) to nitrate (NO₃^-) under physiological conditions and at realistic dose-derived concentrations (K_cat= 2.2 x 10⁶M^-1s^-1). Effectively prevents the oxidation of lipid components by peroxynitrite. Also decomposes superoxide radicals (O₂^?) catalytically. Irradiation of the aqueous solution at 335 nm releases hydroxyl (OH^?) radicals. FeTMPyP can also serve as a potential drug for reactive oxygen species (ROS) detoxification.
Catalyzes the isomerization of peroxynitrite (ONOO^–) to nitrate (NO₃^–) under physiological conditions and at realistic dose-derived concentrations (K_cat= 2.2 x 10⁶M^-1s^-1). Effectively prevents the oxidation of lipid components by peroxynitrite. Also catalytically decomposes superoxide radicals (O₂^·). Irradiation of the aqueous solution at 335 nm releases hydroxyl (OH·) radicals. FeTMPyP can also serve as a potential for drug detoxification of reactive oxygen species (ROS).

包装

10 mg in Plastic ampoule

生化/生理作用

Kcat = 2.2 x 106 M-1s-1 in catalyzing the isomerization of peroxynitrite (ONOO-) to nitrate (NO3-) under physiological conditions
Primary Target
Peroxynitrite (ONOO-)
Product does not compete with ATP.
Reversible: no
Cell permeable: no

警告

Toxicity: Standard Handling (A)

重悬

Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 4 months at -20°C.

其他说明

Lee, J., et al. 1998.J. Am. Chem. Soc.120,7493.
Hunt, J.A., et al. 1997.Chem. Biol.4,845.
Marla, S.S., et al. 1997.Proc. Natl. Acad. Sci. USA94,14243.
Stern, M.K., et al. 1996.J. Am. Chem. Soc.118,8735.
Faraggi, M., et al. 1984.Int. J. Radiat. Biol. Relat. Stud. Phys. Chem. Med.46,703.

法律信息

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

基本信息

经验(实验)分子式	C₄₄H₃₆Cl₅FeN₈
分子量	909.92

半岛bd体育手机客户端性质

质量水平	100
测定	≥90% (TLC)
形式	solid
manufacturer/tradename	Calbiochem^?
储存条件	OK to freeze desiccated (hygroscopic) protect from light
颜色	brown
溶解性	water: 50 mg/mL
运输	ambient
储存温度	?20℃

安全信息

储存分类代码	11 - Combustible Solids
WGK	WGK 1
闪点(F)	Not applicable
闪点(C)	Not applicable