半岛bd体育手机客户端 说明
一般描述
Recombinant, human E-selectin consisting of 535 amino acids minus the transmembrane and cytoplasmic domains expressed in CHO cells. This glycoprotein is transiently expressed on vascular endothelial cell surfaces where it is able to bind to ligands, such as sialyl Lewis x found on leukocytes. This initial binding event is followed by a second interaction involving ICAM and VCAM-1 that leads to vascular penetration and leukocyte invasion into the extracellular matrix tissue.
Recombinant, human E-selectin consisting of 535 amino acids minus the transmembrane and cytoplasmic domains expressed in CHO cells. This glycoprotein is transiently expressed on vascular endothelial cell surfaces where it is able to bind to ligands such as SLexfound on leukocytes. This initial binding event is followed by a second interaction involving ICAM and VCAM-1 that leads to vascular penetration and leukocyte invasion into the extracellular matrix tissue.
包装
50 μg in Plastic ampoule
生化/生理作用
Shown to bind to E-selectin ligands on U937 cells.
警告
Toxicity: Standard Handling (A)
外形
Lyophilized from Dulbecco′s PBS with stabilizer.
重悬
Reconstitute to 1 mg/ml with sterile H?O.
Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 1 month at -20°C.
法律信息
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
半岛bd体育手机客户端 性质
测定 | ≥95% (SDS-PAGE) |
质量水平 | 100 |
形式 | lyophilized |
manufacturer/tradename | Calbiochem? |
储存条件 | OK to freeze |
杂质 | <1 EU/μg Endotoxin (EU/μg of E-Selectin) |
运输 | wet ice |
储存温度 | ?20℃ |
安全信息
储存分类代码 | 11 - Combustible Solids |
WGK | WGK 1 |
Sigma-Aldrich