DL-α-Lipoic Acid, Dihydro--CAS 462-20-4-Calbiochem

半岛bd体育手机客户端 说明

一般描述

An effective antioxidant. Scavenges hypochlorous acid, peroxyl, superoxide, hydroxyl and nitric oxide radicals. Also exhibits prooxidant properties, as demonstrated by its ability to reduce iron ions and to generate reactive sulfur-containing radicals that can damage certain proteins, such as α₁-antiproteinase and creatine kinase. DHLA has recently been shown to inhibit apoptosis in rat thymocytes induced by methylprednisolone and etoposide.
An effective antioxidant. Scavenges hypochlorous acid, peroxyl, superoxide, hydroxyl, and nitric oxide radicals. Also exhibits prooxidant properties, as demonstrated by its ability to reduce iron ions and to generate reactive sulfur-containing radicals that can damage certain proteins, such as α₁-antiproteinase and creatine kinase. DHLA has recently been shown to inhibit apoptosis in rat thymocytes induced by methylprednisolone and etoposide.

包装

50 mg in Plastic ampoule
Packaged under inert gas

生化/生理作用

Product does not compete with ATP.
Reversible: no
Primary Target
Scavenges hypochlorous acid, peroxyl, superoxide, hydroxyl, and nitric oxide radicals
Cell permeable: no

警告

Toxicity: Irritant (B)

其他说明

Packer, L., et al. 1997.Adv. Pharmacol.38,79.
Bustamante, J., et al. 1995.Free Radic. Biol. Med.19,339.
Scott, B.C., et al. 1994.Free Radic. Res.20, 119.

法律信息

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

基本信息

经验(实验)分子式	C8H16O2S2
分子量	208.34
MDL编号	MFCD00166974

半岛bd体育手机客户端 性质

质量水平	100
测定	≥95% (TLC)
形式	liquid
manufacturer/tradename	Calbiochem?
储存条件	OK to freeze protect from light
颜色	light yellow
溶解性	ethanol: 50 mg/mL
运输	ambient
储存温度	2-8℃
InChI	1S/C8H16O2S2/c9-8(10)4-2-1-3-7(12)5-6-11/h7,11-12H,1-6H2,(H,9,10)
InChI key	IZFHEQBZOYJLPK-UHFFFAOYSA-N

安全信息

象形图
警示用语：	Danger
危险声明	H302 - H315 - H317 - H318 - H411
预防措施声明	P261 - P273 - P280 - P301 + P312 - P302 + P352 - P305 + P351 + P338
危险分类	Acute Tox. 4 Oral - Aquatic Chronic 2 - Eye Dam. 1 - Skin Irrit. 2 - Skin Sens. 1
储存分类代码	10 - Combustible liquids
WGK	WGK 2
闪点(F)	348.1 °F - Cleveland open cup
闪点(C)	175.6 ℃ - Cleveland open cup