半岛bd体育手机客户端 说明
一般描述
Cyclic fluorogenic substrate for the quantitative determination of calpain -1 and -2. Also suitable for measuring the peptidase activity of the 20S proteasome. Typical concentrations range from 10 - 100 ?M, depending on assay conditions.
Fluorogenic substrate for the quantitative determination of porcine calpain I and II activity. Also serves as a substrate for other proteases including proteasome. (excitation wavelength: 380 nm; emission wavelength: 460 nm)
包装
25 mg in Plastic ampoule
生化/生理作用
Product does not compete with ATP.
Reversible: no
Primary Target
Calpain -1 and -2
Cell permeable: no
警告
Toxicity: Standard Handling (A)
序列
Suc-Leu-Tyr-AMC
重悬
Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.
其他说明
Seol, J.H., et al. 1989.FEBS Lett.247,197.
Woo, K.M., et al. 1989.J. Biol. Chem.264,2088.
Sasaki, T., et al. 1984.J. Biol. Chem.259,12489.
法律信息
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
基本信息
| 经验(实验)分子式 | C29H31N3O7 |
| 分子量 | 533.57 |
| MDL编号 | MFCD00057900 |
半岛bd体育手机客户端 性质
| 质量水平 | 100 |
| 测定 | ≥95% (TLC) |
| 形式 | solid |
| manufacturer/tradename | Calbiochem? |
| 储存条件 | OK to freeze desiccated protect from light |
| 颜色 | off-white |
| 溶解性 | DMSO: soluble |
| 荧光 | λex~380 nm λem~460 nm |
| 运输 | ambient |
| 储存温度 | ?20℃ |
| InChI | 1S/C29H33N3O8/c1-4-16(2)27(32-24(34)11-12-25(35)36)29(39)31-22(14-18-5-8-20(33)9-6-18)28(38)30-19-7-10-21-17(3)13-26(37)40-23(21)15-19/h5-10,13,15-16,22,27,33H,4,11-12,14H2,1-3H3,(H,30,38)(H,31,39)(H,32,34)(H,35,36)/t16?,22?,27-/m0/s1 |
| InChI key | VSWNAJAOJZXWBM-FTJGSZSVSA-N |
安全信息
| 储存分类代码 | 11 - Combustible Solids |
| WGK | WGK 3 |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
Sigma-Aldrich
m.cnreagent.com
