Calmodulin, His·Tag^?Human, Recombinant

半岛bd体育手机客户端 说明

一般描述

Full-length, recombinant human calmodulin fused to a His?Tag sequence at the N-terminus. Contains four functional Ca²⁺-binding sites (aa 20-31; aa 56-67; aa 93-104; aa 129-140) with EF-hands (aa 7-42; aa 43-78; aa 80-115; aa 116-148); and a ubiquitination site at Lys²¹. This preparation is qualified for use as a substrate for protein tyrosine kinases inin vitroassays. Through its interaction with Ca²⁺, calmodulin mediates the control of a large number of enzymes, including protein kinases and phosphatases. It is expected to be phosphorylated at Thr⁴⁴by CaMK4. In addition, it serves as a substrate for various protein tyrosine kinases.

包装

50 μg in Plastic ampoule
Please refer to vial label for lot-specific concentration.

警告

Toxicity: Standard Handling (A)

外形

In PBS, 0.2% Protease Inhibitor Cocktail Set VII (Cat. No. 539138).

重悬

Following initial thaw, aliquot and freeze (-70°C).

其他说明

Chou, J.J., et al. 2001.Nat. Struct. Biol.8,990.
Lennon, G., et al. 1996.Genomics33,151.

法律信息

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
HIS TAG is a registered trademark of Merck KGaA, Darmstadt, Germany

半岛bd体育手机客户端 性质

质量水平	100
生物来源	human
测定	>90% (SDS-PAGE)
形式	liquid
manufacturer/tradename	Calbiochem?
储存条件	OK to freeze avoid repeated freeze/thaw cycles
运输	wet ice
储存温度	?70℃

安全信息

储存分类代码	12 - Non Combustible Liquids
WGK	WGK 1
闪点(F)	Not applicable
闪点(C)	Not applicable