Anti-WWOX Antibody, clone 12G5

半岛bd体育手机客户端 说明

一般描述

WW domain-containing oxidoreductase (WWOX) is also called Fragile site FRA16D oxidoreductase (FOR). WWOX is a putative oxidoreductase that functions as a tumor suppressor and is involved in apoptosis. WWOX is also required for normal bone development, and inhibits Wnt signaling. WWOX is widely expressed, but is most strongly expressed in testis, prostate, and ovary as well as in cancer cell lines. Certain isoforms (Isoform 5 and isoform 6) are thought to only be expressed in tumor cell lines. WWOX is linked to several cancer types like Esophageal cancer (ESCR).

免疫原

Recombinant protein corresponding to mouse WWOX.

应用

Western Blotting Analysis: 1.0 ?g/mL from a representative lot detected WWOX in 10 ?g of mouse 11 day embreyo and mouse E13-14 Brain tissue lysate.
Immunohistochemistry Analysis: A 1:250 dilution from a representative lot detected WWOX in human cerebellum and human cerebral cortex tissue.
Immunohistochemistry Analysis: A 1:250 dilution from a representative lot detected WWOX in mouse cerebellum and mouse hindbrain tissue.
Anti-WWOX Antibody, clone 12G5 | MABN1594 is an antibody against WWOX Antibody for use in Western Blotting, Immunohistochemistry.
Research Category
Neuroscience
Research Sub Category
Developmental Signaling

质量

Evaluated by Western Blotting in HepG2 cell lysate.

Western Blotting Analysis: 1.0 ?g/mL of this antibody detected WWOX in 10 ?g of HepG2 cell lysate.

目标描述

~46 kDa observed

外形

Purified rat monoclonal IgG2aκ in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
Format: Purified
Protein G Purified

储存及稳定性

Stable for 1 year at 2-8°C from date of receipt.

其他说明

Concentration: Please refer to lot specific datasheet.

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

基本信息

eCl@ss	32160702
NACRES	NA.41

半岛bd体育手机客户端 性质

质量水平	100
生物来源	rat
抗体形式	purified immunoglobulin
antibody product type	primary antibodies
克隆	12G5, monoclonal
species reactivity	human, mouse
technique(s)	immunohistochemistry: suitable western blot: suitable
同位素/亚型	IgG2aκ
NCBI登记号	NP_062519
UniProt登记号	Q91WL8
运输	wet ice

安全信息

储存分类代码	12 - Non Combustible Liquids
WGK	WGK 1
闪点(F)	Not applicable
闪点(C)	Not applicable