Anti-Substance P Antibody, pain

半岛bd体育手机客户端 说明

一般描述

Substance P is a tachykinin family neuropeptide that functions as a neurotransmitter and neuromodulator. In the CNS, Substance P is involved in the regulation of mood, anxiety, sleep, saiety, reinforcement, respiratory rhythm and pain processing. In nociception, the neuropeptide is released at local spinal cord synapse. Recent research now shows substance P is potentially involved in endothelial cell differentiation as well as diverse roles in neuroinflammatory response. The endogenous receptor for Substance P is neurokinin 1 receptor (NK1 receptor), which belongs to the tachykinin receptor sub-family of GPCRs.

特异性

Substance P

应用

RIA:
1:10,000 dilution from a previous lot was used in radioimmunioassay. 80% binding detects at least 5 pg/mL.

Optimal working dilutions must be determined by the end user.
Research Sub Category
Neuroinflammation & Pain
This Anti-Substance P Antibody, pain is validated for use in IH(P), RIA for the detection of Substance P.
Research Category
Neuroscience

质量

Immunohistochemistry(paraffin):
Substance P (AB1566) representative staining pattern/morphology in Alzheimer’s brain. Tissue pretreated with Citrate pH6.0, antigen retrieval. Antibody diluted to 1:100.
IHC-Paraffin Staining With Citrate pH 6.0 Epitope Retrieval: Alzheimer’s Brain.

外形

Unpurified
Rabbit polyclonal serum containing 0.1% sodium azide.

储存及稳定性

Stable for 1 year at -20?C from date of receipt.

分析说明

Control
Spinal Cord.

其他说明

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

法律信息

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

基本信息

eCl@ss	32160702
NACRES	NA.41

半岛bd体育手机客户端 性质

生物来源	rabbit
质量水平	100
抗体形式	serum
antibody product type	primary antibodies
克隆	polyclonal
species reactivity	rat, mouse, human
manufacturer/tradename	Chemicon?
technique(s)	immunohistochemistry: suitable (paraffin) radioimmunoassay: suitable
NCBI登记号	NM_003182.1
UniProt登记号	P20366
运输	dry ice
Gene Information	human ... TAC1(6863)

安全信息

储存分类代码	10 - Combustible liquids
WGK	WGK 1