Anti-S1PR2/EDG5 Antibody, clone 6E8.1

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一般描述

Sphingosine 1-phosphate receptor 2 (S1PR2), otherwise known as EDG5, is a ubiquitous G-protein coupled receptor for lysosphingolipid sphingosine 1-phosphate (S1P). It is coupled to Gi, G12/13, and Gq pathways to regulate a number of second messengers and effector molecules, including cAMP, PLC, MAPK, RhoA, and Rac. S1PR2 mediates the effects of S1P on cell motility and embryonic development, among other cellular processes.

特异性

This antibody recognizes the cytoplasmic domain of S1PR2/EDG5.

免疫原

GST-tagged recombinant protein corresponding to the cytoplasmic domain of human S1PR2/EDG5.

应用

Immunohistochemistry Analysis: A representative lot detected S1PR2/EDG5 in human tonsil, liver, colorectal cancer tissues.
Anti-S1PR2/EDG5 Antibody, clone 6E8.1 detects level of S1PR2/EDG5 & has been published & validated for use in Western Blotting, IHC(P).

质量

Evaluated by Western Blot in human liver tissue lysate.

Western Blot Analysis: 1 ?g/mL of this antibody detected S1PR2/EDG5 in 10 mg of human liver tissue lysate.

目标描述

~35 kDa observed

外形

Purified by Ion-Exchange Chromatography
Format: Purified

其他说明

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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