Anti-SLC12A2 (ab1) antibody produced in chicken

半岛bd体育手机客户端 说明

免疫原

Recombinant solute carrier family 12 (sodium/potassium/chloride transporters), member 2
Immunogen Sequence: GI # 4506975, sequence 800-1000

应用

Anti-SLC12A2 (ab1) antibody produced in chicken is suitable for western blotting analysis at a dilution of 1:500, for tissue or cell staining at a dilution of 1:200.

生化/生理作用

The Na-K-Cl cotransporter (NKCC) is a protein that helps in the active transport of sodium, potassium, and chloride into and out of cells. It couples the movement of Na⁺, K⁺and Cl^-ions across the plasma membrane of most animal cells and plays a central role in cellular homeostasis and human physiology. The proteins play important roles in Na⁺and K⁺concentrations in key physiological systems, including cardiac, vascular, renal, nervous, and sensory systems. NKCC1 levels and functionality are altered in certain disease states. NKCC1 may play a role in glioma cell migration, the precise mechanism by which ion transporter contributes to Glioblastoma (GB) aggressiveness. Its expression levels are found to be significantly higher in GB and anaplastic astrocytoma tissues than in grade II glioma and normal cortex. It also plays a central role in cellular chloride homeostasis and in epithelial salt transport.

外形

Solution in phosphate buffered saline containing 0.02% sodium azide.

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

基本信息

NACRES

NA.41

半岛bd体育手机客户端 性质

生物来源	chicken
偶联物	unconjugated
抗体形式	affinity isolated antibody
antibody product type	primary antibodies
克隆	polyclonal
形式	buffered aqueous solution
species reactivity	mouse, rat, human
manufacturer/tradename	Genway 15-288-22848
technique(s)	western blot: suitable
NCBI登记号	NP_001037.1
UniProt登记号	P55011
运输	wet ice
储存温度	?20℃
Gene Information	human ... SLC12A2(6558)

安全信息

储存分类代码	12 - Non Combustible Liquids
WGK	WGK 1
闪点(F)	Not applicable
闪点(C)	Not applicable
个人防护装备	Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)