Anti-RGS7 antibody produced in chicken

半岛bd体育手机客户端 说明

一般描述

RGS7 (regulator of G-protein signaling 7) is a member of the R7 subfamily of RGS superfamily of regulators, and shares high homology with RGS9-2. It is composed of the catalytic RGS domain, a dishevelled, EGL-10 and pleckstrin (DEP) domain in its N-terminal, along with a G protein γ subunit-like (GGL) domain. It is both a soluble cytosolic protein as well as a membrane protein.

免疫原

Immunogen Sequence: GI # 11140809, sequence 227-262
Recombinant regulator of G-protein signalling 7

应用

Anti-RGS7 antibody produced in chicken is suitable for western blotting analysis at a dilution of 1:500, for tissue or cell staining at a dilution of 1:200.

生化/生理作用

Regulator of G-protein signaling 7 belongs to a subfamily of regulator of G protein signaling (RGS) proteins, which modulate G protein signaling by acting as GTPase-activating proteins for G protein α-subunits. RGS7 exists as a dimer with the G protein β(5)-subunit. It plays a major role in the pathogenesis of panic disorder (PD). RGS7 has a potential role in neurons communicating between classical heterotrimeric G protein subunits and/or their effectors at the plasma membrane and the cell nucleus. It helps in regulating signaling by μ-opioid receptor (MOR) and dopamine D2 receptor (D2R) and are implicated in drug addiction, movement disorders and nociception.

外形

Solution in phosphate buffered saline containing 0.02% sodium azide.

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

半岛bd体育手机客户端 性质

生物来源	chicken
偶联物	unconjugated
抗体形式	affinity isolated antibody
antibody product type	primary antibodies
克隆	polyclonal
形式	buffered aqueous solution
species reactivity	mouse, human, rat
manufacturer/tradename	Genway 15-288-21310
technique(s)	western blot: suitable
NCBI登记号	NP_002915.1
UniProt登记号	P49802
运输	wet ice
储存温度	?20℃
Gene Information	human ... RGS7(6000)

安全信息

储存分类代码	12 - Non Combustible Liquids
WGK	WGK 1
闪点(F)	Not applicable
闪点(C)	Not applicable
个人防护装备	Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)