Anti-PTPRF antibody produced in chicken

半岛bd体育手机客户端 说明

免疫原

Recombinant protein tyrosine phosphatase, receptor type, F isoform 1
Immunogen Sequence: GI # 4506311, sequence 1151-1225

应用

Anti-PTPRF antibody produced in chicken is suitable for western blotting analysis at a dilution of 1:500, for tissue or cell staining at a dilution of 1:200.

生化/生理作用

Receptor-type tyrosine-protein phosphatase F is an enzyme encoded by the PTPRF gene in humans. It localizes to adherens junctions and may be involved in the regulation of epithelial cell-cell contacts, peptide growth factor signaling and the canonical Wnt pathway. PTPRF induction occurs by cell-cell contact during cell proliferation that activates ERK-dependent proliferation signaling to prevent cell hyperproliferation and tumor initiation. It acts as a crucial regulator of the sensitivity of two key insulin signalling pathways to insulin. PTPRF regulates cell proliferation, response to growth factors and cellular adhesion. Mutation in the gene is associated with breast cancer.

外形

Solution in phosphate buffered saline containing 0.02% sodium azide.

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

基本信息

NACRES

NA.41

半岛bd体育手机客户端 性质

生物来源	chicken
偶联物	unconjugated
抗体形式	affinity isolated antibody
antibody product type	primary antibodies
克隆	polyclonal
形式	buffered aqueous solution
species reactivity	human, mouse, rat
manufacturer/tradename	Genway 15-288-21469
technique(s)	western blot: suitable
NCBI登记号	NP_002831.1
UniProt登记号	P10586
运输	wet ice
储存温度	?20℃
Gene Information	human ... PTPRF(5792)

安全信息

储存分类代码	12 - Non Combustible Liquids
WGK	WGK 1
闪点(F)	Not applicable
闪点(C)	Not applicable
个人防护装备	Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)